Recombinant Human HLA-DOA, GST-tagged
Cat.No. : | HLA-DOA-13814H |
Product Overview : | Recombinant Human HLA-DOA protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 25-221a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | HLA-DOA major histocompatibility complex, class II, DO alpha [ Homo sapiens ] |
Official Symbol : | HLA-DOA |
Synonyms : | HLA-DOA; major histocompatibility complex, class II, DO alpha; HLA DNA, HLA DZA; HLA class II histocompatibility antigen, DO alpha chain; HLA D0 alpha; HLA-D0-alpha; MHC DN-alpha; MHC DZ alpha; lymphocyte antigen; MHC class II antigen DOA; major histocompatibility complex, class II, DN alpha; HLADZ; HLA-DNA; HLA-DZA; |
Gene ID : | 3111 |
mRNA Refseq : | NM_002119 |
Protein Refseq : | NP_002110 |
MIM : | 142930 |
UniProt ID : | P06340 |
Chromosome Location : | 6p21.3 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; |
Function : | MHC class II receptor activity; |
Products Types
◆ Recombinant Protein | ||
HLA-DOA-4838H | Recombinant Human HLA-DOA Protein, GST-tagged | +Inquiry |
HLA-DOA-232H | Recombinant Human major histocompatibility complex, class II, DO alpha, His-tagged | +Inquiry |
◆ Lysates | ||
HLA-DOA-5502HCL | Recombinant Human HLA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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