Recombinant Human HOXD8, His-tagged HOXD8-13915H

Recombinant Human HOXD8, His-tagged


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Recombinant Human HOXD8, His-tagged

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Cat.No. : HOXD8-13915H
Product Overview : Recombinant Human HOXD8 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5 end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.
Source : E.coli
Species : Human
Tag : His
Protein length : 1-289a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : HOXD8 homeobox D8 [ Homo sapiens ]
Official Symbol : HOXD8
Synonyms : HOXD8; homeobox D8; homeo box D8 , HOX4, HOX4E; homeobox protein Hox-D8; Hox-4.5; homeo box 4E; homeo box D8; homeobox protein 5.4; homeobox protein Hox-4E; homeobox protein Hox-5.4; HOX4; HOX4E; HOX5.4;
Gene ID : 3234
mRNA Refseq : NM_001199746
Protein Refseq : NP_001186675
MIM : 142985
UniProt ID : P13378
Chromosome Location : 2q31.1
Function : sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity;

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