Recombinant Human IKZF3 protein, His-tagged
Cat.No. : | IKZF3-14138H |
Product Overview : | Recombinant Human IKZF3 protein(209-509 aa), fused with His tag, was expressed in E.coli. |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole. |
Protein Length : | 209-509 aa |
AA Sequence : | RSYKQRSSLEEHKERCRTFLQSTDP GDTASAEARHIKAEMGSERALVLDR LASNVAKRKSSMPQKFIGEKRHCFD VNYNSSYMYEKESELIQTRMMDQAI NNAISYLGAEALRPLVQTPPAPTSE MVPVISSMYPIALTRAEMSNGAPQE LEKKSIHLPEKSVPSERGLSPNNSG HDSTDTDSNHEERQNHIYQQNHMVL SRARNGMPLLKEVPRSYELLKPPPI CPRDSVKVINKEGEVMDVYRCDHCR VLFLDYVMFTIHMGCHGFRDPFECN MCGYRSHDRYEFSSHIARGEHRALL K |
Purity : | 85%, by SDS-PAGE with Coomassie Brilliant Blue staining. |
Storage : | Short-term storage: Store at 2-8°C for (1-2 weeks). Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles. |
Reconstitution : | Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage. Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage. |
Gene Name : | IKZF3 IKAROS family zinc finger 3 (Aiolos) [ Homo sapiens ] |
Official Symbol : | IKZF3 |
Synonyms : | IKZF3; IKAROS family zinc finger 3 (Aiolos); zinc finger protein, subfamily 1A, 3 (Aiolos) , ZNFN1A3; zinc finger protein Aiolos; Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos); AIO; AIOLOS; ZNFN1A3; |
Gene ID : | 22806 |
mRNA Refseq : | NM_001257408 |
Protein Refseq : | NP_001244337 |
MIM : | 606221 |
UniProt ID : | Q9UKT9 |
Products Types
◆ Recombinant Protein | ||
IKZF3-4488M | Recombinant Mouse IKZF3 Protein, His (Fc)-Avi-tagged | +Inquiry |
IKZF3-487H | Recombinant Human IKZF3 Protein, MYC/DDK-tagged | +Inquiry |
Ikzf3-3499M | Recombinant Mouse Ikzf3 Protein, Myc/DDK-tagged | +Inquiry |
IKZF3-258H | Recombinant Human IKZF3 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
IKZF3-4121H | Recombinant Human IKZF3 Protein (Met1-Lys509), C-MYC/DDK tagged | +Inquiry |
◆ Lysates | ||
IKZF3-5251HCL | Recombinant Human IKZF3 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionSeveral clinical trials are exploring the potential of targeting IKZF3 protein in the treatment of autoimmune diseases and cancer, with the aim of developing novel therapeutic strategies.
IKZF3 protein regulates the proliferation and survival of cancer cells, and its dysregulation has been associated with the development of various types of cancer.
IKZF3 protein interacts with various cellular pathways involved in immune regulation, cell proliferation, and apoptosis, making it a potential target for therapeutic interventions.
Genetic variations in the IKZF3 gene have been linked to susceptibility to autoimmune diseases and may impact clinical outcomes in patients with these conditions.
Research has suggested that IKZF3 protein expression levels may have prognostic value in certain types of cancer, and further studies are needed to validate its clinical significance.
Customer Reviews (3)
Write a reviewWith its high purity and bioactivity, IKZF3 protein ensures reliable and consistent results in a wide range of experimental applications.
the IKZF3 protein is carefully characterized, and its functional properties are well-documented.
The IKZF3 protein is of exceptional quality and is perfectly suited to meet the experimental needs of researchers.
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