Recombinant Human GIMAP5, His-tagged

• Cat.No.: GIMAP5-2319H
• Product Overview: Recombinant human GIMAP5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: GIMAP5 is a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. GIMAP5 is an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 2mM DTT
• Molecular Mass: 34.4 kDa
• Protein length: 307aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGGFQRG KYGTMAEGRS EDNLSATPPA LRIILVGKTG CGKSATGNSI LGQPVFESKL RAQSVTRTCQ VKTGTWNGRK VLVVDTPSIF ESQADTQELY KNIGDCYLLS APGPHVLLLV IQLGRFTAQD TVAIRKVKEV FGTGAMRHVV ILFTHKEDLG GQALDDYVAN TDNCSLKDLV RECERRYCAF NNWGSVEEQR QQQAELLAVI ERLGREREGS FHSNDLFLDA QLLQRTGAGA CQEDYRQYQA KVEWQVEKHK QELRENESNW AYKALLRVKH LMLLHYE
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml

Gene Information

• Gene Name: GIMAP5 GTPase, IMAP family member 5 [ Homo sapiens ]
• Official Symbol: GIMAP5
• Synonyms: GIMAP5; GTPase, IMAP family member 5; IAN4L1, immune associated nucleotide 4 like 1 (mouse); GTPase IMAP family member 5; HIMAP3; immunity associated protein 3; immune associated nucleotide 4 like 1; immunity-associated nucleotide 5 protein; inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5; IAN4; IAN5; IROD; IAN-5; IMAP3; IAN4L1; FLJ11296
• Gene ID: 55340
• mRNA Refseq: NM_018384
• Protein Refseq: NP_060854
• MIM: 608086
• UniProt ID: Q96F15
• Chromosome Location: 7q36.1
• Function: GTP binding; nucleotide binding