"DBR1" Related Products

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Recombinant Human DBR1, His-tagged

Cat.No.: DBR1-2340H
Product Overview: Recombinant human DBR1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: DBR1 is an RNA lariat debranching enzyme that hydrolyzes 2"-5" prime branched phosphodiester bonds. The encoded protein specifically targets the bonds at the branch point of excised lariat intron RNA, converting them to linear molecules that are then degraded. This protein may also be involved in retroviral replication.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT.
Molecular Mass: 38 kDa (Molecular size on SDS-PAGE will appear higher)
Protein length: 340aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHVKFAAL MQHQAKDKGQ TARATKFLAL DKCLPHRDFL QILEIEHDPS APDYLEYDIE WLTILRATDDLINVTGRLWN MPENNGLHAR WDYSATEEGM KEVLEKLNHD LKVPCNFSVT AACYDPSKPQ TQMQLIHRIN PQTTEFCAQL GIIDINVRLQ KSKEEHHVCG EYEEQDDVES NDSGEDQSEY NTDTSALSSI NPDEIMLDEE EDEDSIVSAH SGMNTPSVEP SDQASEFSAS FSDVRILPGSMIVSSDDTVD STIDREGKPG GTVESGNGED LTKVPLKRLS DEHEPEQRKK IKRRNQAIYA AVDDDDDDAA
Purity: >90% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml
Gene Name: DBR1 debranching enzyme homolog 1 (S. cerevisiae) [ Homo sapiens ]
Official Symbol: DBR1
Synonyms: DBR1; debranching enzyme homolog 1 (S. cerevisiae); debranching enzyme (S. Cerevisiae) homolog 1; lariat debranching enzyme; RNA lariat debranching enzyme;
Gene ID: 51163
mRNA Refseq: NM_016216
Protein Refseq: NP_057300
MIM: 607024
UniProt ID: Q9UK59
Chromosome Location: 3q22.3
Function: RNA lariat debranching enzyme activity; hydrolase activity, acting on ester bonds; metal ion binding;

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