Recombinant Human DBR1 Protein, GST-tagged

• Cat.No.: DBR1-2374H
• Product Overview: Human DBR1 full-length ORF ( NP_057300.2, 1 a.a. - 544 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is an RNA lariat debranching enzyme that hydrolyzes 2'-5' prime branched phosphodiester bonds. The encoded protein specifically targets the bonds at the branch point of excised lariat intron RNA, converting them to linear molecules that are then degraded. This protein may also be involved in retroviral replication. [provided by RefSeq, Nov 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 88 kDa
• AA Sequence: MRVAVAGCCHGELDKIYETLALAER RGPGPVDLLLCCGDFQAVRNEADLR CMAVPPKYRHMQTFYRYYSGEKKAP VLTLFIGGNHEASNHLQELPYGGWV APNIYYLGLAGVVKYRGVRIGGISG IFKSHDYRKGHFECPPYNSSTIRSI YHVRNIEVYKLKQLKQPIDIFLSHD WPRSIYHYGNKKQLLKTKSFFRQEV ENNTLGSPAASELLEHLKPTYWFSA HLHVKFAALMQHQAKDKGQTARATK FLALDKCLPHRDFLQILEIEHDPSA PDYLEYDIEWLTILRATDDLINVTG RLWNMPENNGLHARWDYSATEEGMK EVLEKLNHDLKVPCNFSVTAACYDP SKPQTQMQLIHRINPQTTEFCAQLG IIDINVRLQKSKEEHHVCGEYEEQD DVESNDSGEDQSEYNTDTSALSSIN PDEIMLDEEEDEDSIVSAHSGMNTP SVEPSDQASEFSASFSDVRILPGSM IVSSDDTVDSTIDREGKPGGTVESG NGEDLTKVPLKRLSDEHEPEQRKKI KRRNQAIYAAVDDDDDDAA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DBR1 debranching enzyme homolog 1 (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: DBR1
• Synonyms: DBR1; debranching enzyme homolog 1 (S. cerevisiae); debranching enzyme (S. Cerevisiae) homolog 1; lariat debranching enzyme; RNA lariat debranching enzyme
• Gene ID: 51163
• mRNA Refseq: NM_016216
• Protein Refseq: NP_057300
• MIM: 607024
• UniProt ID: Q9UK59