Recombinant Human GAGE2A, His-tagged

• Cat.No.: GAGE2A-2337H
• Product Overview: Recombinant human GAGE2A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: GAGE2A belongs to a multigene family expressed in a large variety of tumors whereas in normal tissues, expression is restricted to germ cells. These genes organized in clustered repeats, have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT.
• Molecular Mass: 15 kDa (Molecular size on SDS-PAGE will appear higher)
• Protein length: 139aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSWRGRS TYRPRPRRYV EPPEMIGPMR PEQFSDEVEP ATPEEGEPAT QRQDPAAAQE GQDEGASAGQGPKPEAHSQE QGHPQTGCEC EDGPDGQEMD PPNPEEVKTP EEGEKQSQC
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: GAGE2A G antigen 2A [ Homo sapiens ]
• Official Symbol: GAGE2A
• Synonyms: CT4.2; GAGE2; GAGE-2; GAGE-2A; G antigen 2A; 4099; Ensembl:ENSG00000189064; MGC96883, MGC96930, MGC96942; G antigen 2A/2B;cancer/testis antigen 4.2;cancer/testis antigen family 4, member 2
• Gene ID: 729447
• mRNA Refseq: NM_001127212.1
• Protein Refseq: NP_001120684.1
• MIM: 300720
• UniProt ID: Q6NT46
• Chromosome Location: Xp11.23
• Function: molecular_function