Active Recombinant Human CSF3R
Cat.No. : | CSF3R-9295H |
Product Overview : | Recombinant Human CSF3R was expressed in CHO Cells. |
- Specification
- Gene Information
- Related Products
Description : | Human Granulocyte Colony Stimulating Factor (G-CSF) contains internal disulfide bonds. Among the family of colony-stimulating factors, Granulocyte Colony Stimulating Factor (G-CSF) is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of Granulocyte Colony Stimulating Factor (G-CSF) can be induced by bacterial endotoxins, TNF, Interleukin-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of Granulocyte Colony Stimulating Factor (G-CSF). In epithelial, endothelial, and fibroblastic cells, the secretion of Granulocyte Colony Stimulating Factor (G-CSF) is induced by Interleukin-17. |
Source : | CHO Cells |
Species : | Human |
Form : | Lyophilized after extensive dialysis against PBS. |
Bio-activity : | ED50< 0.1 ng/ml, determined by the dose-dependent stimulation of the proliferation of murine m-nfs-60 cells, corresponding to a specific activity of>1 x 107 units/mg. |
Molecular Mass : | 18.7kDa, observed by non-reducing SDS-PAGE. |
AA Sequence : | Thr27-Pro200. |
Endotoxin : | <0.2 eu/μg, determined by lal>0.2> |
Purity : | >95% as analyzed by SDS-PAGE and HPLC. |
Storage : | Lyophilized recombinant protein remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhG-CSF should be stable up to 1 week at 4°C or up to 2 months at -20°C. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/ml. |
Gene Name : | CSF3R colony stimulating factor 3 receptor (granulocyte) [ Homo sapiens ] |
Official Symbol : | CSF3R |
Synonyms : | CSF3R; colony stimulating factor 3 receptor (granulocyte); CD114; granulocyte colony-stimulating factor receptor; GCSFR; G-CSF-R; CD114 antigen; G-CSF receptor; |
Gene ID : | 1441 |
mRNA Refseq : | NM_000760 |
Protein Refseq : | NP_000751 |
MIM : | 138971 |
UniProt ID : | Q99062 |
Chromosome Location : | 1p35-p34.3 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; Pathways in cancer, organism-specific biosystem; |
Function : | cytokine receptor activity; receptor activity; |
Products Types
◆ Recombinant Protein | ||
CSF3R-260H | Recombinant Human CSF3R Protein, Fc-tagged | +Inquiry |
CSF3R-1975H | Recombinant Human CSF3R Protein, GST-tagged | +Inquiry |
CSF3R-1041H | Recombinant Human CSF3R protein(Met1-Pro621) | +Inquiry |
CSF3R-259H | Recombinant Human CSF3R Protein, His-tagged | +Inquiry |
CSF3R-023H | Recombinant Human CSF3R Protein, C-His-tagged | +Inquiry |
◆ Lysates | ||
CSF3R-1803HCL | Recombinant Human CSF3R cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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