"PPP1R2" Related Products

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Recombinant human PPP1R2, His-tagged

Cat.No.: PPP1R2-2438H
Product Overview: Recombinant human PPP1R2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: PPP1R2 is an inhibitor of protein-phosphatase 1 and forms heterodimer with PP1. Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex. Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.
Source: E.coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl(pH8.0) containing 30% glycerol, 0.15M NaCl, 1mM DTT
Molecular Mass: 21kDa (189aa), confirmed by MALDI-TOF
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAASTAS HRPIKGILKN KTSTTSSMVA SAEQPRGNVD EELSKKSQKW DEMNILATYH PADKDYGLMKIDEPSTPYHS MMGDDEDACS DTEATEAMAP DILARKLAAA EGLEPKYRIQ EQESSGEEDS DLSPEEREKK RQFEMKRKLH YNEGLNIKLA RQLISKDLH
Purity: >85% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.25 mg/ml (determined by Bradford assay)
Gene Name: PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 [ Homo sapiens ]
Official Symbol: PPP1R2
Synonyms: PPP1R2; protein phosphatase 1, regulatory (inhibitor) subunit 2; protein phosphatase inhibitor 2; IPP2; phosphatase inhibitor 2; phosphoprotein phosphatase; IPP-2; MGC87148;
Gene ID: 5504
mRNA Refseq: NM_006241
Protein Refseq: NP_006232
MIM: 601792
UniProt ID: P41236
Chromosome Location: 3q29
Function: protein binding; protein serine/threonine phosphatase inhibitor activity;

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