"LAG3" Related Products


Recombinant Human LAG3, Fc-tagged

Cat.No.: LAG3-102H
Product Overview: The sequence coding for the 4 extracellular Ig-like domains of human LAG-3 (D1-D4) is fused to the Fc portion of human IgG1.
Description: Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
Source: CHO cells
Species: Human
Tag: Fc
Form: Liquid. In PBS.
Bio-activity: Inhibits binding of MAb to LAG-3 (human) to LAG-3. Induces maturation of human dendritic cells.
Molecular Mass: ~80kDa (SDS-PAGE)
Endotoxin: <0.1EU/μg purified protein
Purity: ≥99% (SDS-PAGE)
Applications: Flow Cytometry: Detection of MHC class II molecules in combination with fluorescently labeled antibodies to IgG1.
Stability: Stable for at least 6 months after receipt when stored at -20°C.
Storage: Short Term Storage +4°C Long Term Storage -20°C
Concentration: 0.5 mg/ml
Gene Name: LAG3 lymphocyte-activation gene 3 [ Homo sapiens (human) ]
Official Symbol: LAG3
Synonyms: LAG3; CD223; lymphocyte-activation gene 3; lymphocyte activation gene 3 protein
Gene ID: 3902
mRNA Refseq: NM_002286
Protein Refseq: NP_002277
MIM: 153337
UniProt ID: P18627
Chromosome Location: 12p13.32
Function: MHC class II protein binding; antigen binding; transmembrane signaling receptor activity

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