- Human(13)
- Rhesus Macaque(1)
Human CCL18, Biotin-tagged
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| Cat.No. : | CCL18-113H |
| Product Overview : | It is a synthetic Protein with Biotin tag. |
| Description : | Pulmonary and activation-regulated chemokine (PARC)-1, which has also been identified as alternative macrophage activation-associated CC chemokine-1 (AMAC-1), Macrophage Inflammatory Protein-4 (MIP-4) and dendritic cell chemokine (DC-CK1), is a novel CC chemokine which shares 61% sequence homology with MIP-1 . PARC-1 cDNA encodes an 89 amino acid protein which contains a 20 amino acid signal peptide that is cleaved to generate the mature 69 amino acid protein lacking glycosylation sites. PARC-1 is highly expressed in lung and placenta but is not expressed in epidermal Langerhans cells. |
| Species : | Human |
| Tag : | Biotin |
| Form : | Lyophilized |
| Bio-activity : | Activity measured by ability of the protein to induce chemotaxis in T-lymphocytes. ED50 for this measurement is generally 0.5-2 μg/ml. |
| Applications : | Activity Assay |
| Storage : | Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles |
| Reconstitution : | Recommended reconstitution in sterile phosphate buffered saline which contains at least 0.1% human or bovine serum albumin to prepare a stocksolution of no less than 20 μg/ml and vortex thoroughly. |
| Gene Name : | CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) [ Homo sapiens ] |
| Official Symbol : | CCL18 |
| Synonyms : | CCL18; chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated); SCYA18, small inducible cytokine subfamily A (Cys Cys), member 18, pulmonary and activation regulated; C-C motif chemokine 18; AMAC 1; CKb7; DC CK1; DCCK1; MIP 4; PARC; CC chemokine PARC; CC chemokine ligand 18; chemokine (C-C), dendritic; dendritic cell chemokine 1; small inducible cytokine A18; small-inducible cytokine A18; macrophage inflammatory protein 4; pulmonary and activation-regulated chemokine; alternative macrophage activation-associated CC chemokine 1; small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated; AMAC1; MIP-4; AMAC-1; DC-CK1; SCYA18; |
| Gene ID : | 6362 |
| mRNA Refseq : | NM_002988 |
| Protein Refseq : | NP_002979 |
| MIM : | 603757 |
| UniProt ID : | P55774 |
| Chromosome Location : | 17q11.2 |
| Pathway : | Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
| Function : | chemokine activity; protein binding; |
◆ Recombinant Protein
| CCL18-2892H | Recombinant Human CCL18 Protein, MYC/DDK-tagged | +Inquiry |
| CCL18-0616H | Recombinant Human CCL18 Protein, GST-Tagged | +Inquiry |
| CCL18-200H | Recombinant Human CCL18 protein | +Inquiry |
| CCL18-252H | Recombinant Human Chemokine (C-C Motif) Ligand 18, MIgG2a Fc-tagged | +Inquiry |
| CCL18-681R | Recombinant Rhesus monkey CCL18 Protein, His-tagged | +Inquiry |
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