Human CCL18, Biotin-tagged CCL18-113H

Human CCL18, Biotin-tagged


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Human CCL18, Biotin-tagged

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Cat.No. : CCL18-113H
Product Overview : It is a synthetic Protein with Biotin tag.
Description : Pulmonary and activation-regulated chemokine (PARC)-1, which has also been identified as alternative macrophage activation-associated CC chemokine-1 (AMAC-1), Macrophage Inflammatory Protein-4 (MIP-4) and dendritic cell chemokine (DC-CK1), is a novel CC chemokine which shares 61% sequence homology with MIP-1 . PARC-1 cDNA encodes an 89 amino acid protein which contains a 20 amino acid signal peptide that is cleaved to generate the mature 69 amino acid protein lacking glycosylation sites. PARC-1 is highly expressed in lung and placenta but is not expressed in epidermal Langerhans cells.
Species : Human
Tag : Biotin
Form : Lyophilized
Bio-activity : Activity measured by ability of the protein to induce chemotaxis in T-lymphocytes. ED50 for this measurement is generally 0.5-2 μg/ml.
Applications : Activity Assay
Storage : Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Reconstitution : Recommended reconstitution in sterile phosphate buffered saline which contains at least 0.1% human or bovine serum albumin to prepare a stocksolution of no less than 20 μg/ml and vortex thoroughly.
Gene Name : CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) [ Homo sapiens ]
Official Symbol : CCL18
Synonyms : CCL18; chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated); SCYA18, small inducible cytokine subfamily A (Cys Cys), member 18, pulmonary and activation regulated; C-C motif chemokine 18; AMAC 1; CKb7; DC CK1; DCCK1; MIP 4; PARC; CC chemokine PARC; CC chemokine ligand 18; chemokine (C-C), dendritic; dendritic cell chemokine 1; small inducible cytokine A18; small-inducible cytokine A18; macrophage inflammatory protein 4; pulmonary and activation-regulated chemokine; alternative macrophage activation-associated CC chemokine 1; small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated; AMAC1; MIP-4; AMAC-1; DC-CK1; SCYA18;
Gene ID : 6362
mRNA Refseq : NM_002988
Protein Refseq : NP_002979
MIM : 603757
UniProt ID : P55774
Chromosome Location : 17q11.2
Pathway : Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function : chemokine activity; protein binding;

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