"IL17BR" Related Products

Recombinant Human IL17BR, Fc-tagged

Cat.No.: IL17BR-212H
Product Overview: A DNA sequence encoding the human IL17BR (NP_061195.2) (Met1-Gly289) was expressed with the Fc region of human IgG1 at the C-terminus.
Description: Interleukin-17 receptor B, also known as IL-17 receptor B, IL-17RB, Cytokine receptor-like 4, IL-17 receptor homolog 1, Interleukin-17B receptor, IL-17B receptor, IL17RB and CRL4, is a secreted and single-pass type I membrane protein which contains one SEFIR domain. IL-17B receptor / IL17RB is expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines. IL-17B receptor / IL17RB is a receptor for the proinflammatory cytokines IL17B and IL17E. IL-17B receptor / IL17RB does not bind to IL17 and IL17C. IL-17B receptor / IL17RB may play a role in controlling the growth and / or differentiation of hematopoietic cells. IL-17B receptor / IL17RB has also been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E.
Source: Human Cells
Species: Human
Tag: Fc
Predicted N Terminal: Arg 18
Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.
Molecular Mass: The recombinant human IL17BR/Fc is a disulfide-linked homodimer. The reduced monomer comprises 513 amino acids and has a predicted molecular mass of 56.9 kDa. The apparent molecular mass of the protein is approximately 67 kDa in SDS-PAGE under reducing conditions.
Endotoxin: < 1.0 eu per μg of the protein as determined by the lal
Purity: >85 % as determined by SDS-PAGE
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name: IL17RB?interleukin 17 receptor B [?Homo sapiens?(human) ]
Official Symbol: IL17RB
Synonyms: IL17RB; CRL4; EVI27; IL17BR; IL17RH1; interleukin 17 receptor B; interleukin-17 receptor B; IL-17RB; IL-17Rh1; IL-17B receptor; IL-17 receptor B; cytokine receptor CRL4; IL-17 receptor homolog 1; cytokine receptor-like 4; interleukin 17B receptor; interle
Gene ID: 55540
mRNA Refseq: NM_018725
Protein Refseq: NP_061195
MIM: 605458
UniProt ID: Q9NRM6
Chromosome Location: 3p21.1
Pathway: Cytokine-cytokine receptor interaction
Function: cytokine receptor activity

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