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Recombinant Human TSPAN8, His tagged

Cat.No. : TSPAN8-400H
Product Overview : Recombinant Human TSPAN8 (P19075) (Lys110-Asn205), fused with an N-terminal polyhistidine tag, was produced in Human Cells.
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  • Gene Information
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Source : Human Cells
Species : Human
Tag : His
Predicted N Terminal : His
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
Molecular Mass : The recombinant human TSPAN8 comprises 116 amino acids and has a predicted molecular mass of 13.4 kDa. The apparent molecular mass of the protein is approximately 17 and 13 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : (87.8+10.7) % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : TSPAN8 tetraspanin 8 [ Homo sapiens ]
Official Symbol : TSPAN8
Gene ID : 7103
mRNA Refseq : NM_004616
Protein Refseq : NP_004607
MIM : 600769
UniProt ID : P19075
Chromosome Location : 12q14.1-q21.1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the significance of TSPAN8 protein in disease diagnosis and prognosis? 11/14/2019

Detecting the expression level of TSPAN8 protein can help with the diagnosis and prognosis of certain diseases. For example, in colon cancer patients, high expression of the TSPAN8 protein is often associated with malignancy and poor prognosis of the tumor.

What is the role of the interaction of the TSPAN8 protein with other proteins in the disease? 10/13/2019

The interaction of the TSPAN8 protein with other proteins plays an important role in a variety of diseases. For example, in colon cancer, the TSPAN8 protein can interact with integrins, promoting the proliferation and migration of tumor cells. Therefore, understanding these interactions is important for understanding the pathogenesis of disease and the selection of therapeutic targets.

What are the possible applications of TSPAN8 protein in future medical and scientific research? 09/19/2019

With the in-depth understanding of the structure and function of TSPAN8 protein, the drug development and application of TSPAN8 protein will be more extensive in the future. For example, the development of drugs targeting the TSPAN8 protein may be used to treat tumors, autoimmune diseases, and neurological diseases.

Are there polymorphisms in the TSPAN8 gene, and are these polymorphisms associated with disease? 06/02/2019

There are a variety of polymorphisms in the TSPAN8 gene that may affect the structure and function of proteins and are associated with the development of certain diseases. For example, one study found that a polymorphism in the TSPAN8 gene was associated with susceptibility to esophageal cancer in northern Chinese populations.

Is TSPAN8 protein involved in apoptosis? 04/25/2019

Studies have shown that the TSPAN8 protein can participate in the apoptosis process. It can regulate the permeability of mitochondrial membranes by interacting with members of the Bcl-2 family, thereby influencing the conduction of apoptosis signals.

How is the activity of TSPAN8 protein regulated? 01/13/2019

The activity of TSPAN8 protein is affected by a variety of regulators, including phosphorylation modification, ubiquitination modification, etc. These regulators can influence the structure and function of the TSPAN8 protein and thus its biological function.

Customer Reviews (3)

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Reviews
04/30/2022

    Due to wide range of applications of TSPAN8 is impressive, and no matter what field, it can play an important role.

    11/06/2020

      Band position of TSPAN8 in Western blot was consistent with the expected, showing good target recognition ability.

      06/29/2019

        The stability of TSPAN8 is excellent, and its performance remains stable after many repeated uses, showing good product quality.

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