Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human AMIGO2, His tagged

Cat.No. : AMIGO2-568H
Product Overview : Recombinant Human AMIGO2 (NP_862830.1) (Met1-Thr398), fused with a polyhistidine tag at the C-terminus, was produced in Human Cells.
  • Specification
  • Gene Information
  • Related Products
Source : Human Cells
Species : Human
Tag : His
Predicted N Terminal : Val 40
Form : Lyophilized from sterile PBS, pH 7.4Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
Molecular Mass : The recombinant human AMIGO2 consists of 370 amino acids and predicts a molecular mass of 42.3 KDa. It migrates as an approximately 58-63 KDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >95 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : AMIGO2 adhesion molecule with Ig-like domain 2 [ Homo sapiens ]
Official Symbol : AMIGO2
Gene ID : 347902
mRNA Refseq : NM_181847
Protein Refseq : NP_862830
UniProt ID : Q86SJ2
Chromosome Location : 12q13.11

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (10)

Ask a question
Is there a correlation between AMIGO2 expression levels and neurological disorders? 03/25/2022

Altered expression or dysregulation of AMIGO2 has been associated with neurological disorders, including autism spectrum disorders and epilepsy, highlighting its potential role in disease pathogenesis.

What is the expression pattern of AMIGO2 in the developing and adult brain? 12/13/2021

AMIGO2 exhibits a dynamic expression pattern in the developing and adult brain, with high expression in regions involved in neuronal development, such as the cortex, hippocampus, and cerebellum.

What are the functional consequences of AMIGO2 knockout or overexpression in neuronal development and function? 11/07/2021

Knockout or overexpression studies of AMIGO2 have revealed its essential role in neuronal development and function, impacting processes such as neurite outgrowth, synaptogenesis, and neuronal survival.

Can AMIGO2 modulate synaptic plasticity and neurotransmission? 03/11/2021

AMIGO2 is involved in modulating synaptic plasticity and neurotransmission, regulating the activity and surface expression of neurotransmitter receptors and contributing to the refinement of synaptic connectivity.

How does AMIGO2 influence dendritic arborization and synaptic connectivity? 09/19/2020

AMIGO2 influences dendritic arborization and synaptic connectivity, promoting dendritic branching and the formation of mature dendritic spines, which are crucial for synaptic transmission and plasticity.

Does AMIGO2 play a role in myelination and oligodendrocyte development? 09/11/2020

AMIGO2 plays a role in myelination and oligodendrocyte development, contributing to proper myelin sheath formation and the maturation of oligodendrocytes.

Can manipulation of AMIGO2 expression or activity be a potential therapeutic approach for neurological conditions? 09/07/2020

Modulation of AMIGO2 expression or activity holds potential as a therapeutic approach for neurological conditions, and further investigation into its specific mechanisms and interactions may unveil novel strategies for intervention and treatment.

What is the role of AMIGO2 in axon guidance and pathfinding? 12/27/2017

AMIGO2 is involved in axon guidance and pathfinding, guiding axons to their appropriate targets during neuronal development, and contributing to the establishment of neuronal circuitry.

How does AMIGO2 contribute to neuronal migration during brain development? 11/08/2017

AMIGO2 plays a critical role in neuronal migration during brain development, regulating the proper positioning and layering of neurons in the developing cerebral cortex.

Does AMIGO2 interact with other cell adhesion molecules or signaling proteins, and what are the downstream signaling pathways involved? 10/06/2017

AMIGO2 interacts with various cell adhesion molecules and signaling proteins, including members of the immunoglobulin superfamily and growth factor receptors, activating downstream signaling pathways involved in cell adhesion, cytoskeletal remodeling, and synaptic plasticity.

Customer Reviews (3)

Write a review
Reviews
05/17/2021

    Versatility in multiple assay formats and platforms.

    09/24/2020

      Excellent reproducibility in protein expression profiling.

      11/02/2017

        Stable reagents for long-term storage and repeated use.

        Ask a Question for All AMIGO2 Products

        Required fields are marked with *

        My Review for All AMIGO2 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends