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Recombinant Cynomolgus TNFSF4, Fc tagged

Cat.No. : TNFSF4-67C
Product Overview : Recombinant Cynomolgus TNFSF4 (F7FL80) (Gln51-Leu183), fused with the Fc region of mouse IgG1 at the N-terminus, was produced in Human Cells.
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  • Gene Information
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Source : Human Cells
Species : Cynomolgus
Tag : Fc
Predicted N Terminal : Asp
Form : Lyophilized from sterile PBS, pH 7.4.Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
Molecular Mass : The recombinant cynomolgus TNFSF4 is a disulfide-linked homodimer. The reduced monomer comprises 369 amino acids and has a calculated molecular mass of 42 KDa.The apparent molecular mass of it is approximately 48 KDa respectively in SDS-PAGE.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >85 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4oC before opening to recover the entire contents.
Gene Name : TNFSF4?tumor necrosis factor (ligand) superfamily, member 4 [Macaca fascicularis?(crab-eating macaque) ]
Official Symbol : TNFSF4
Gene ID : 102141877
mRNA Refseq : XM_005540022
Protein Refseq : XP_005540079
Chromosome Location : 1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How do genetic variations in TNFSF4 affect immune function? 01/09/2022

Genetic changes in TNFSF4 affect immune regulation and autoimmune disease susceptibility.

What is the primary role of TNFSF4 in immune system regulation? 08/16/2021

TNFSF4 (OX40L) regulates immune responses and T-cell activation.

How does TNFSF4 contribute to inflammatory responses? 05/11/2020

It activates T-cells, stimulating inflammatory cytokine production.

What role does TNFSF4 play in autoimmune disorders? 09/12/2019

TNFSF4 is implicated in autoimmune disease development by promoting immune cell activation.

How does TNFSF4 interact with other cytokines and receptors in the immune system? 06/09/2019

TNFSF4 interacts with OX40 and other receptors, influencing immune signaling.

What potential therapeutic applications arise from targeting TNFSF4 in immune-related diseases? 10/04/2018

Targeting TNFSF4 could treat autoimmune and inflammatory diseases by modulating the immune system.

What is the impact of altered TNFSF4 activity on chronic inflammation? 03/29/2017

Altered TNFSF4 activity contributes to chronic inflammation.

Customer Reviews (3)

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Reviews
12/28/2022

    Efficient service, accelerates research productivity.

    05/13/2018

      Outstanding accuracy, essential for research quality.

      02/12/2018

        Trusted for research integrity, a critical research asset.

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