Recombinant Human ACSS3, His-tagged
Cat.No. : | ACSS3-18H |
Product Overview : | Recombinant Human Acyl-CoA Synthetase Short-Chain Family Member 3 Mitochondrial/ACSS3 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala30-Ala686) of Human ACSS3 fused with a polyhistidine tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | Acyl-CoA Synthetase Short-Chain Family Member 3 Mitochondrial (ACSS3) is a member of the ATP-dependent AMP-binding enzyme family. ACSS3 localizes to the mitochondrion and catalyzes acetate and CoA into diphosphate and acetyl-CoA using the ATP. ACSS3 activates acetate for lipid synthesis use or for energy generation. Two isoforms of the human protein are produced by alternative splicing. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
AA Sequence : | AGAALRALVVPGPRGGLGGRGCRAL SSGSGSEYKTHFAASVTDPERFWGK AAEQISWYKPWTKTL ENKHSPSTRWFVEGMLNICYNAVDR HIENGKGDKIAIIYDSPVTNTKATF TYKEVLEQVSKLAGV LVKHGIKKGDTVVIYMPMIPQAMYT MLACARIGAIHSLIFGGFASKELSS RIDHVKPKVVVTASF GIEPGRRVEYVPLVEEALKIGQHKP DKILIYNRPNMEAVPLAPGRDLDWD EEMAKAQSHDCVPVL SEHPLYILYTSGTTGLPKGVIRPTG GYAVMLHWSMSSIYGLQPGEVWWAA SDLGWVVGHSYICYG PLLHGNTTVLYEGKPVGTPDAGAYF RVLAEHGVAALFTAPTAIRAIRQQD PGAALGKQYSLTRFK TLFVAGERCDVETLEWSKNVFRVPV LDHWWQTETGSPITASCVGLGNSKT PPPGQAGKSVPGYNV MILDDNMQKLKARCLGNIVVKLPLP PGAFSGLWKNQEAFKHLYFEKFPGY YDTMDAGYMDEEGYL YVMSRVDDVINVAGHRISAGAIEES ILSHGTVADCAVVGKEDPLKGHVPL ALCVLRKDINATEEQ VLEEIVKHVRQNIGPVAAFRNAVFV KQLPKTRSGKIPRSALSAIVNGKPY KITSTIEDPSIFGHV EEMLKQAVDHHHHHH |
Endotoxin : | Less than 0.1 ng/μg (1 IEU/μg). |
Purity : | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
Gene Name : | ACSS3 acyl-CoA synthetase short-chain family member 3 [ Homo sapiens ] |
Official Symbol : | ACSS3 |
Synonyms : | ACSS3; acyl-CoA synthetase short-chain family member 3; acyl-CoA synthetase short-chain family member 3, mitochondrial; FLJ21963; AMP-binding enzyme, 33217; |
Gene ID : | 79611 |
mRNA Refseq : | NM_024560 |
Protein Refseq : | NP_078836 |
MIM : | 614356 |
UniProt ID : | Q9H6R3 |
Chromosome Location : | 12q21.31 |
Pathway : | Metabolic pathways, organism-specific biosystem; Propanoate metabolism, organism-specific biosystem; Propanoate metabolism, conserved biosystem; acetate conversion to acetyl-CoA, organism-specific biosystem; ethanol degradation II, organism-specific biosystem; ethanol degradation IV, organism-specific biosystem; oxidative ethanol degradation III, organism-specific biosystem; |
Function : | ATP binding; acetate-CoA ligase activity; ligase activity; nucleotide binding; |
Products Types
◆ Recombinant Protein | ||
ACSS3-280M | Recombinant Mouse ACSS3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Acss3-1514M | Recombinant Mouse Acss3 Protein, Myc/DDK-tagged | +Inquiry |
ACSS3-265H | Recombinant Human ACSS3 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACSS3-1237M | Recombinant Mouse ACSS3 Protein | +Inquiry |
ACSS3-9329H | Recombinant Human ACSS3, His-tagged | +Inquiry |
◆ Lysates | ||
ACSS3-9067HCL | Recombinant Human ACSS3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (10)
Ask a questionACSS3 has been found to be upregulated in certain cancers and is associated with tumor growth, progression, and metabolic reprogramming.
Yes, ACSS3 can influence gene expression through its role in protein acetylation, which can modify histones and transcription factors.
ACSS3 activity is sensitive to cellular energy levels, particularly levels of ATP (adenosine triphosphate), which is an indicator of energy availability.
ACSS3 expression can be regulated by various factors, including nutrient availability, cellular energy status, and transcriptional control.
Acetyl-CoA is involved in various metabolic processes, including the citric acid cycle (Krebs cycle), fatty acid synthesis, and protein acetylation.
Recent studies have linked dysregulation of ACSS3 to various diseases, including cancer, obesity, and metabolic disorders.
Yes, there are commercially available antibodies and kits that can be used for detecting ACSS3 protein in biological samples, such as Western blotting or immunohistochemistry.
Yes, ACSS3 protein can be produced using recombinant DNA technology by cloning the ACSS3 gene into an expression vector and expressing it in a suitable host organism, such as bacteria or yeast.
The activity of ACSS3 can be measured through enzymatic assays that assess the conversion of acetate to acetyl-CoA in vitro, using purified ACSS3 protein or cell lysates.
Common techniques for purifying ACSS3 protein include affinity chromatography, size exclusion chromatography, and ion exchange chromatography.
Customer Reviews (5)
Write a reviewUnbeatable price for the exceptional quality of the protein. Service was impeccable.
Outstanding quality at an affordable price. Impressed with the value for money.
Versatile and compatible. Fits various experimental setups."
"The performance of this protein is truly remarkable. Its consistent and reliable results have significantly contributed to the success of our research endeavors.
It eliminates background noise and provides clear and interpretable data.
Ask a Question for All ACSS3 Products
Required fields are marked with *
My Review for All ACSS3 Products
Required fields are marked with *
Inquiry Basket