Recombinant Human SH3KBP1, His-tagged

• Cat.No.: SH3KBP1-57H
• Product Overview: Recombinant Human SH3 Domain-Containing Kinase-Binding Protein 1/SH3KBP1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Lys665) of Human SH3KBP1 fused with a 6His tag at the C-terminus.

Specification

• Description: SH3 Domain-Containing Kinase-Binding Protein 1 (SH3KBP1) contains 3 SH3 domains. SH3KBP1 is widely expressed in many tissues, it is also expressed in some cancer cell lines. SH3KBP1 plays a role in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases. SH3KBP1 is involved in regulation of ligand-dependent endocytosis of the IgE receptor and in the regulation of cellular stress response via the MAPK pathways. SH3KBP1 is also required for the control of cell shape and migration.
• Source: HEK293
• Species: Human
• Tag: His
• AA Sequence: MVEAIVEFDYQAQHDDELTISVGEI ITNIRKEDGGWWEGQINGRRGLFPD NFVREIKKEMKKDPL TNKAPEKPLHEVPSGNSLLSSETIL RTNKRGERRRRRCQVAFSYLPQNDD ELELKVGDIIEVVGE VEEGWWEGVLNGKTGMFPSNFIKEL SGESDELGISQDEQLSKSSLRETTG SESDGGDSSSTKSEG ANGTVATAAIQPKKVKGVGFGDIFK DKPIKLRPRSIEVENDFLPVEKTIG KKLPATTATPDSSKT EMDSRTKSKDYCKVIFPYEAQNDDE LTIKEGDIVTLINKDCIDVGWWEGE LNGRRGVFPDNFVKL LPPDFEKEGNRPKKPPPPSAPVIKQ GAGTTERKHEIKKIPPERPEMLPNR TEEKERPEREPKLDL QKPSVPAIPPKKPRPPKTNSLSRPG ALPPRRPERPVGPLTHTRGDSPKID LAGSSLSGILDKDLS DRSNDIDLEGFDSVVSSTEKLSHPT TSRPKATGRRPPSQSLTSSSLSSPD IFDSPSPEEDKEEHI SLAHRGVDASKKTSKTVTISQVSDN KASLPPKPGTMAAGGGGPAPLSSAV PSPLSSSLGTAGHRA NSPSLFGTEGKPKMEPAASSQAAVE ELRTQVRELRSIIETMKDQQKREIK QLLSELDEEKKIRLR LQMEVNDIKKALQSKVDHHHHHH
• Endotoxin: Less than 0.1 ng/μg (1 IEU/μg).
• Purity: Greater than 95% as determined by reducing SDS-PAGE.

Gene Information

• Gene Name: SH3KBP1 reserved [ Homo sapiens ]
• Official Symbol: SH3KBP1
• Synonyms: SH3KBP1; reserved
• Gene ID: 94010