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Recombinant Human DPEP1, His-tagged

Cat.No. : DPEP1-77H
Product Overview : Recombinant Human Dipeptidase 1/DPEP1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Asp17-Ser385) of Human DPEP1 fused with a 6His tag at the C-terminus.
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Description : Dipeptidase 1 (DPEP1) is a kidney membrane enzyme that belongs to the peptidase M19 family. DPEP1 is a homodimer and is inhibited by L-penicillamine. DPEP1 hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates. DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem. DPEP1 may play an important role in the regulation of leukotriene activity. DPEP1 expression in cancer is significantly higher than that in normal tissue. However, DPEP1 expression decreased with pathological differentiation, lymph-node and distant metastasis.
Source : HEK293
Species : Human
Tag : His
AA Sequence : DFFRDEAERIMRDSPVIDGHNDLPW QLLDMFNNRLQDERANLTTLAGTHT NIPKLRAGFVGGQFW SVYTPCDTQNKDAVRRTLEQMDVVH RMCRMYPETFLYVTSSAGIRQAFRE GKVASLIGVEGGHSI DSSLGVLRALYQLGMRYLTLTHSCN TPWADNWLVDTGDSEPQSQGLSPFG QRVVKELNRLGVLID LAHVSVATMKATLQLSRAPVIFSHS SAYSVCASRRNVPDDVLRLVKQTDS LVMVNFYNNYISCTN KANLSQVADHLDHIKEVAGARAVGF GGDFDGVPRVPEGLEDVSKYPDLIA ELLRRNWTEAEVKGA LADNLLRVFEAVEQASNLTQAPEEE PIPLDQLGGSCRTHYGYSSVDHHHH HH
Endotoxin : Less than 0.1 ng/μg (1 IEU/μg).
Purity : Greater than 95% as determined by reducing SDS-PAGE.
Publication :
Pulmonary Delivery of Engineered Exosomes to Suppress Postoperative Melanoma Lung Metastasis through Preventing Premetastatic Niche Formation (2021)

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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