Recombinant Human MIIP, His-tagged


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Recombinant Human MIIP, His-tagged

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Cat.No. : MIIP-141H
Product Overview : Recombinant Human Migration and Invasion-Inhibitory Protein/MIIP is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Pro388) of Human MIIP fused with a polyhistidine tag at the C-terminus.
Description : Migration and Invasion-Inhibitory Protein (MIIP) was initially discovered in a yeast two-hybrid screen for proteins that interact with and inhibit the migration and invasion-promoting protein insulin-like growth factor binding protein 2 (IGFBP2). It is reported that MIIP not only modulates IGFBP2 but also regulates microtubule by binding to and inhibiting HDAC6, a class 2 histone deacetylase that deacetylates α-tubulin, heat-shock protein 90 (HSP90), and cortactin. In addition, MIIP also regulates the mitosis checkpoint, another microtubule-associated process.
Source : HEK293
Species : Human
Tag : His
Endotoxin : Less than 0.1 ng/μg (1 IEU/μg).
Purity : Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Gene Name : MIIP migration and invasion inhibitory protein [ Homo sapiens ]
Official Symbol : MIIP
Synonyms : MIIP; migration and invasion inhibitory protein; migration and invasion-inhibitory protein; FLJ12438; IIp45; invasion inhibitory protein 45; IGFBP2-binding protein; invasion-inhibitory protein 45; IIP45; RP5-1077B9.4; FLJ38609;
Gene ID : 60672
mRNA Refseq : NM_021933
Protein Refseq : NP_068752
MIM : 608772
UniProt ID : Q5JXC2
Chromosome Location : 1p36.22

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