Recombinant Human MIIP, His-tagged
Cat.No. : | MIIP-141H |
Product Overview : | Recombinant Human Migration and Invasion-Inhibitory Protein/MIIP is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Pro388) of Human MIIP fused with a polyhistidine tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | Migration and Invasion-Inhibitory Protein (MIIP) was initially discovered in a yeast two-hybrid screen for proteins that interact with and inhibit the migration and invasion-promoting protein insulin-like growth factor binding protein 2 (IGFBP2). It is reported that MIIP not only modulates IGFBP2 but also regulates microtubule by binding to and inhibiting HDAC6, a class 2 histone deacetylase that deacetylates α-tubulin, heat-shock protein 90 (HSP90), and cortactin. In addition, MIIP also regulates the mitosis checkpoint, another microtubule-associated process. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
AA Sequence : | MVEAEELAQLRLLNLELLRQLWVGQ DAVRRSVARAASESSLESSSSYNSE TPSTPETSSTSLSTS CPRGRSSVWGPPDACRGDLRDVARS GVASLPPANCQHQESLGRPRPHSAP SLGTSSLRDPEPSGR LGDPGPQEAQTSRSILAQQSKLSKP RVTFSEESAVPERSWRLRPYLGYDW IAGSLDTSSSITSQP EAFFSKLQEFRETNKEECICSHPEP QLPGLRESSGSGVEEDHECVYCYRV NRRLFPVPVDPGTPC RLCRTPRDQQGPGTLAQPAHVRVSI PLSILEPPHRYHIHRRKSFDASDTL ALPRHCLLGWDIFPP KSEKSSAPRNLDLWSSVSAEAQHQK LSGTSSPFHPASPMQMLPPTPTWSV PQVPRPHVPRQKPVD HHHHHH |
Endotoxin : | Less than 0.1 ng/μg (1 IEU/μg). |
Purity : | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
Gene Name : | MIIP migration and invasion inhibitory protein [ Homo sapiens ] |
Official Symbol : | MIIP |
Synonyms : | MIIP; migration and invasion inhibitory protein; migration and invasion-inhibitory protein; FLJ12438; IIp45; invasion inhibitory protein 45; IGFBP2-binding protein; invasion-inhibitory protein 45; IIP45; RP5-1077B9.4; FLJ38609; |
Gene ID : | 60672 |
mRNA Refseq : | NM_021933 |
Protein Refseq : | NP_068752 |
MIM : | 608772 |
UniProt ID : | Q5JXC2 |
Chromosome Location : | 1p36.22 |
Products Types
◆ Recombinant Protein | ||
Miip-2442M | Recombinant Mouse Miip Protein, Myc/DDK-tagged | +Inquiry |
MIIP-1411H | Recombinant Human MIIP Protein, His (Fc)-Avi-tagged | +Inquiry |
MIIP-3341R | Recombinant Rat MIIP Protein, His (Fc)-Avi-tagged | +Inquiry |
MIIP-5560M | Recombinant Mouse MIIP Protein, His (Fc)-Avi-tagged | +Inquiry |
MIIP-5340H | Recombinant Human MIIP Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
MIIP-4314HCL | Recombinant Human MIIP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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