Recombinant Human SERPINE2 protein, His-tagged
Cat.No. : | SERPINE2-187H |
Product Overview : | Recombinant Human SERPINE2 (Ser20-Pro397) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | SERPINE2 is also known as Glia-derived nexin (GDN), Peptidase inhibitor 7 (PI7), Protease nexin 1(PN1). SERPINE2 is a secreted glycoprotein which belongs to the serpin family. SerpinE1 is the primary physiological inhibitor of the two plasminogen activators urokinase (uPA) and tissue plasminogen activator (tPA). PAI-1/GDN is also implicated in adipose tissue development. It suggests that PAI-1 inhibitors serve in the control of atherothrombosis. Defects in Serpin E1/PN1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) which is characterized by abnormal bleeding due to SerpinE1 defect in the plasma. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Ser20 |
Form : | Lyophilized from 0.22 μm filtered solution in 20 mM Sodium Acetate, 100 mM NaCl, pH6.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 42.7 kDa. The protein migrates as 45-48 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Ser20-Pro397 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >92% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | SERPINE2 |
Official Symbol : | SERPINE2 |
Synonyms : | SERPINE2; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; PI7, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; glia-derived nexin; GDN; glial derived nexin 1; nexin; PN1; PNI; serpin E2; protease nexin I; peptidase inhibitor 7; glial-derived neurite promoting factor; PI7; PI-7; PN-1; DKFZp686A13110 |
Gene ID : | 5270 |
mRNA Refseq : | NM_001136528 |
Protein Refseq : | NP_001130000 |
MIM : | 177010 |
UniProt ID : | P07093 |
Products Types
◆ Recombinant Protein | ||
SERPINE2-8057M | Recombinant Mouse SERPINE2 Protein, His (Fc)-Avi-tagged | +Inquiry |
SERPINE2-1981H | Recombinant Human SERPINE2 Protein, His (Fc)-Avi-tagged | +Inquiry |
SERPINE2-574H | Recombinant Human SERPINE2 Protein, His-tagged | +Inquiry |
Serpine2-5791M | Recombinant Mouse Serpine2 Protein, Myc/DDK-tagged | +Inquiry |
SERPINE2 -94R | Recombinant Rabbit PAI-1 wild type latent | +Inquiry |
◆ Lysates | ||
SERPINE2-1937HCL | Recombinant Human SERPINE2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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