"PDIA3" Related Products

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Recombinant Human PDIA3, His-tagged

Cat.No.: PDIA3-120H
Product Overview: The protein was expressed as 6*his-tagged fusion protein by E.Coli and puri?ed by Ni-sepharose.
Description: This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
Source: E.coli
Species: Human
Tag: His
Protein length: 161-505aa
Storage: The protein is stored in PBS bu?er at -20 oC. Repeated freezethaw cycles should be avoided.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: PDIA3 protein disulfide isomerase family A, member 3 [ Homo sapiens(human) ]
Official Symbol: PDIA3
Synonyms: PDIA3; P58; ER60; ERp57; ERp60; ERp61; GRP57; GRP58; PI-PLC; HsT17083; protein disulfide isomerase family A, member 3; protein disulfide-isomerase A3; ER protein 57; ER protein 60; phospholipase C-alpha; 58 kDa microsomal protein; disulfide isomerase ER-60; endoplasmic reticulum P58; 58 kDa glucose-regulated protein; glucose regulated protein, 58kDa; protein disulfide isomerase-associated 3; endoplasmic reticulum resident protein 57; endoplasmic reticulum resident protein 60; EC 5.3.4.1
Gene ID: 2923
mRNA Refseq: NM_005313
Protein Refseq: NP_005304
MIM: 602046
UniProt ID: P30101
Chromosome Location: 15q15
Pathway: Adaptive Immune System; Antigen processing and presentation; Calnexin/calreticulin cycle
Function: cysteine-type endopeptidase activity; electron carrier activity; protein binding

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