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Recombinant Human NEUROG3, His-tagged

Cat.No. : NEUROG3-5002H
Product Overview : Recombinant human NeuroG3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
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  • Gene Information
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Description : NEUROG3 is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
Molecular Mass : 25.1 kDa (234aa)
AA Sequence : MGSSHHHHHH SSGLVPRGSH MTPQPSGAPT VQVTRETERS FPRASEDEVT CPTSAPPSPT RTRGNCAEAE EGGCRGAPRK LRARRGGRSR PKSELALSKQ RRSRRKKAND RERNRMHNLN SALDALRGVL PTFPDDAKLT KIETLRFAHN YIWALTQTLR IADHSLYALE PPAPHCGELG SPGGSPGDWG SLYSPVSQAG SLSPAASLEE RPGLLGATSS ACLSPGSLAF SDFL
Purity : >85% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.25 mg/ml (determined by Bradford assay)
Gene Name : NEUROG3 neurogenin 3 [ Homo sapiens ]
Official Symbol : NEUROG3
Synonyms : NEUROG3; neurogenin 3; neurogenin-3; Atoh5; bHLHa7; Math4B; ngn3; protein atonal homolog 5; class A basic helix-loop-helix protein 7; NGN-3;
Gene ID : 50674
mRNA Refseq : NM_020999
Protein Refseq : NP_066279
MIM : 604882
UniProt ID : Q9Y4Z2
Chromosome Location : 10q21.3
Pathway : Developmental Biology, organism-specific biosystem; Maturity onset diabetes of the young, organism-specific biosystem; Maturity onset diabetes of the young, conserved biosystem; Notch-mediated HES/HEY network, organism-specific biosystem; Regulation of beta-cell development, organism-specific biosystem; Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells, organism-specific biosystem; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells, organism-specific biosystem;
Function : DNA binding; double-stranded DNA binding; transcription coactivator activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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