Recombinant Human UQCRC1, His-tagged

• Cat.No.: UQCRC1-5098H
• Product Overview: Recombinant human UQCRC1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Description: UQCRC1 is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
• Molecular Mass: 51.8kDa (471aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSEFTATFA QALQFVPETQ VSLLDNGLRV ASEQSSQPTC TVGVWIDVGS RFETEKNNGA GYFLEHLAFK GTKNRPGSAL EKEVESMGAH LNAYSTREHT AYYIKALSKD LPKAVELLGD IVQNCSLEDS QIEKERDVIL REMQENDASM RDVVFNYLHA TAFQGTPLAQ AVEGPSENVR KLSRADLTEY LSTHYKAPRM VLAAAGGVEH QQLLDLAQKH LGGIPWTYAE DAVPTLTPCR FTGSEIRHRD DALPFAHVAI AVEGPGWASP DNVALQVANA IIGHYDCTYG GGVHLSSPLA SGAVANKLCQ SFQTFSICYA ETGLLGAHFV CDRMKIDDMM FVLQGQWMRL CTSATESEVA RGKNILRNAL VSHLDGTTPV CEDIGRSLLT YGRRIPLAEW ESRIAEVDAS VVREICSKYI YDQCPAVAGY GPIEQLPDYN RIRSGMFWLR F
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: UQCRC1 ubiquinol-cytochrome c reductase core protein I [ Homo sapiens ]
• Official Symbol: UQCRC1
• Synonyms: UQCRC1; ubiquinol-cytochrome c reductase core protein I; cytochrome b-c1 complex subunit 1, mitochondrial; D3S3191; QCR1; UQCR1; core protein I; complex III subunit 1; ubiquinol-cytochrome-c reductase complex core protein 1
• Gene ID: 7384
• mRNA Refseq: NM_003365
• Protein Refseq: NP_003356
• MIM: 191328
• UniProt ID: P31930
• Chromosome Location: 3p21
• Pathway: Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Cytochrome bc1 complex, organism-specific biosystem; Cytochrome bc1 complex, conserved biosystem; Electron Transport Chain, organism-specific biosystem
• Function: catalytic activity; metal ion binding; metalloendopeptidase activity; protein complex binding; ubiquinol-cytochrome-c reductase activity; zinc ion binding