"IRF5" Related Products

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Recombinant Human IRF5, His-tagged

Cat.No. : IRF5-5121H
Product Overview : Recombinant human IRF5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description : IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
Molecular Mass : 10.7 kDa (101aa) confirmed by MALDI-TOF
AA Sequence : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSPPTL QPPTLQPPVV LGPPAPDPSP LAPPPGNPAG FRELLSEVLE PGPLPASLPP AGEQLLPDLL I
Purity : >85 % by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.25 mg/ml (determined by Bradford assay)
Gene Name : IRF5 interferon regulatory factor 5 [ Homo sapiens ]
Official Symbol : IRF5
Synonyms : IRF5; interferon regulatory factor 5; IRF-5; SLEB10;
Gene ID : 3663
mRNA Refseq : NM_001098627
Protein Refseq : NP_001092097
MIM : 607218
UniProt ID : Q13568
Chromosome Location : 7q32
Pathway : Apoptosis, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; Interferon alpha/beta signaling, organism-specific biosystem; Interferon gamma signaling, organism-specific biosystem;
Function : protein binding; regulatory region DNA binding; sequence-specific DNA binding transcription factor activity;

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