Recombinant Human LOXL3, GST-tagged

• Cat.No.: LOXL3-132H
• Product Overview: Recombinant human LOXL3 (526-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: LOXL3 is a member of the lysyl oxidase gene family. This family is essential to the biogenesis of connective tissue. The lysyl oxidase gene family encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. LOXL3 is highly expressed in central nervous system, uterus, heart, and leukocyte. LOXL3 plays an important role in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis.
• Source: Sf9 insect cells using baculovirus
• Species: Human
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~54 kDa
• Purity: >90% by densitometry
• Applications: Western Blot
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 μg/μl

Gene Information

• Gene Name: LOXL3 lysyl oxidase-like 3 [ Homo sapiens ]
• Official Symbol: LOXL3
• Synonyms: LOXL3; lysyl oxidase-like 3; lysyl oxidase homolog 3; lysyl oxidase-like protein 3; LOXL
• Gene ID: 84695
• mRNA Refseq: NM_032603
• Protein Refseq: NP_115992
• MIM: 607163
• UniProt ID: P58215
• Chromosome Location: 2p13
• Function: copper ion binding; copper ion binding; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; protein-lysine 6-oxidase activity; scavenger receptor activity