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Recombinant Human MGRN1, GST-tagged

Cat.No. : MGRN1-179H
Product Overview : Recombinant human MGRN1 (2-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
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  • Gene Information
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Description : MGRN1 or mahogunin ring finger 1, E3 ubiquitin protein ligase is a C3HC4 RING-containing protein with E3 ubiquitin ligase activity in vitro. MGRN1 gene encodes 4 mRNA isoforms that contain a central C3HC4 RING domain as the only recognizable protein motif and regions flanking the RING domain and the N-terminal region of the protein are also conserved between vertebrate and invertebrate genome and MGRN1 is highly expressed in brain. MGRN1 has been detected in the adrenal cortex in kidney and its role may relate to the trafficking and/or degradation of the melanocortin 2 receptor.
Source : Sf9 insect cells using baculovirus
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Molecular Mass : ~96 kDa
Purity : >90% by densitometry
Applications : Kinase Assay, Western Blot
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 μg/μl
Gene Name : MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase [ Homo sapiens ]
Official Symbol : MGRN1
Synonyms : MGRN1; mahogunin ring finger 1, E3 ubiquitin protein ligase; mahogunin, ring finger 1; E3 ubiquitin-protein ligase MGRN1; KIAA0544; RNF156; RING finger protein 156; mahogunin RING finger protein 1; probable E3 ubiquitin-protein ligase MGRN1;
Gene ID : 23295
mRNA Refseq : NM_001142289
Protein Refseq : NP_001135761
MIM : 607559
UniProt ID : O60291
Chromosome Location : 16p13
Pathway : Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem;
Function : ligase activity; metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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