"TFRC" Related Products

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Native Human Transferrin Receptor

Cat.No.: TFRC-249H
Product Overview: Purified Native Human Serum Transferrin Receptor.
Description: Transferrin receptor (TfR) is a carrier protein for transferrin. It is needed for the import of iron into the cell and is regulated in response to intracellular iron concentration. Transferrin Receptor imports iron by internalizing the transferrin-iron complex through receptor-mediated endocytosis.Low iron concentrations promote increased levels of transferrin receptor, to increase iron intake into the cell. Thus, transferrin receptor maintains cellular iron homeostasis
Source: Human Serum
Species: Human
Form: Liquid - 25 mM TRIS buffer, 0.15 M NaCl, 0.09% Sodium Azide, pH: 8.0 + or - 0.2
Storage: Store at -20 °C.
Gene Name: TFRC transferrin receptor (p90, CD71) [ Homo sapiens ]
Official Symbol: TFRC
Synonyms: TFRC; transferrin receptor (p90, CD71); transferrin receptor protein 1; CD71; TFR1; T9; TR; TFR; p90; TRFR;
Gene ID: 7037
mRNA Refseq: NM_001128148
Protein Refseq: NP_001121620
MIM: 190010
UniProt ID: P02786
Chromosome Location: 3q26.2-qter
Pathway: Clathrin derived vesicle budding, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem;
Function: Hsp70 protein binding; chaperone binding; peptidase activity; receptor activity; transferrin receptor activity;

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