Recombinant Human ACE2, FLAG-tagged

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Recombinant Human ACE2, FLAG-tagged

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Cat.No. : ACE2-67H
Product Overview : Signal peptide sequence and the extracellular domain of human ACE2 (aa 1-740) are fused at the C-terminus to a FLAG-tag.
Description : ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.
Source : HEK293 Cells
Species : Human
Tag : FLAG
Form : Liquid. 0.2μm-filtered solution in PBS.
Bio-activity : Converts angiotensin I to angiotensin-(1-9).
Molecular Mass : ~90kDa (SDS-PAGE)
Endotoxin : <0.1eu g purified protein (lal test; lonza).>
Purity : ≥90% (SDS-PAGE)
Stability : Working aliquots are stable for up to 3 months when stored at -20°C.
Storage : Short Term Storage: +4°C; Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Concentration : 1mg/ml
Gene Name : ACE2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 [ Homo sapiens ]
Official Symbol : ACE2
Synonyms : ACE2; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin-converting enzyme 2; metalloprotease MPROT15; ACE-related carboxypeptidase; angiotensin I converting enzyme 2; angiotensin-converting enzyme homolog; ACEH;
Gene ID : 59272
mRNA Refseq : NM_021804
Protein Refseq : NP_068576
MIM : 300335
UniProt ID : Q9BYF1
Chromosome Location : Xp22
Pathway : ACE Inhibitor Pathway, organism-specific biosystem; Protein digestion and absorption, organism-specific biosystem; Protein digestion and absorption, conserved biosystem; Renin-angiotensin system, organism-specific biosystem; Renin-angiotensin system, conserved biosystem;
Function : carboxypeptidase activity; endopeptidase activity; glycoprotein binding; metal ion binding; NOT metallopeptidase activity; peptidase activity; NOT peptidyl-dipeptidase activity; viral receptor activity; zinc ion binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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