Recombinant Human ICAM1, Fc-tagged

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Human ICAM1, Fc-tagged

Recombinant Human ICAM1, Fc-tagged

ICAM1 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : ICAM1-146H
Product Overview : The extracellular domain of human CD54 [ICAM-1] (aa 28-480) is fused to the N-terminus of the Fc region of a mutant human IgG1.
Description : Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac1. CD54 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-γ, TNF-α, IL-1β and LPS. Soluble CD54 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, LAD, cancer and transplantation.
Source : CHO Cells
Species : Human
Tag : Fc
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Shows the biological function of the CD54 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
Purity : ≥98% (SDS-PAGE)
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Storage : Short Term Storage: +4°C; Long Term Storage: -20°C. Avoid freeze/thaw cycles.
Gene Name : ICAM1 intercellular adhesion molecule 1 [ Homo sapiens ]
Official Symbol : ICAM1
Synonyms : ICAM1; intercellular adhesion molecule 1; BB2; CD54; human rhinovirus receptor; ICAM-1; cell surface glycoprotein P3.58; major group rhinovirus receptor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; P3.58;
Gene ID : 3383
mRNA Refseq : NM_000201
Protein Refseq : NP_000192
MIM : 147840
UniProt ID : P05362
Chromosome Location : 19p13.3-p13.2
Pathway : Adaptive Immune System, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem;
Function : cell surface binding; integrin binding; protein binding; receptor activity; transmembrane signaling receptor activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Verification Code Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy