Recombinant Human MMP23B, His-tagged

• Cat.No.: MMP23B-167H
• Product Overview: MMP23B, 79-254aa, Human, His tag, E.coli

Specification

• Description: MMP23B is a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Recombinant human MMP23B protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
• Molecular Mass: 22.6 kDa (199aa)
• Protein length: 79-254aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSYTLTPAR LRWDHFNLTY RILSFPRNLL SPRETRRALA AAFRMWSDVS PFSFREVAPE QPSDLRIGFY PINHTDCLVS ALHHCFDGPT GELAHAFFPP HGGIHFDDSE YWVLGPTRYS WKKGVWLTDL VHVAAHEIGH ALGLMHSQHG RALMHLNATL RGWKALSQDE LWGLHRLYG
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: MMP23B matrix metallopeptidase 23B [ Homo sapiens ]
• Official Symbol: MMP23B
• Synonyms: MMP23B; matrix metallopeptidase 23B; matrix metalloproteinase 23B , MMP22; matrix metalloproteinase-23; femalysin; matrix metalloproteinase 22; matrix metalloproteinase in the female reproductive tract; MIFR; MIFR 1; MMP-21; MMP-22; MMP-23; matrix metalloproteinase-21; matrix metalloproteinase-22; matrix metalloproteinase 23B; MMP22; MIFR-1; MMP23A
• Gene ID: 8510
• mRNA Refseq: NM_006983
• Protein Refseq: NP_008914
• MIM: 603321
• UniProt ID: O75900
• Chromosome Location: 1p36.3
• Pathway: Matrix Metalloproteinases, organism-specific biosystem
• Function: metal ion binding; metalloendopeptidase activity; metalloendopeptidase activity; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; zinc ion binding; zinc ion binding