Recombinant Human RANBP3, His-tagged

• Cat.No.: RANBP3-221H
• Product Overview: RANBP3, 235-445aa, Human, His tag, E.coli

Specification

• Description: RANBP3 is a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This protein plays a role in nuclear export as part of a heteromeric complex. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Recombinant human RANBP3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol
• Molecular Mass: 25.5 kDa (234aa) confirmed by MALDI-TOF
• Protein length: 235-445aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSISSSLEN STNSADASSN KFVFGQNMSE RVLSPPKLNE VSSDANRENA AAESGSESSS QEATPEKESL AESAAAYTKA TARKCLLEKV EVITGEEAES NVLQMQCKLF VFDKTSQSWV ERGRGLLRLN DMASTDDGTL QSRLVMRTQG SLRLILNTKL WAQMQIDKAS EKSIRITAMD TEDQGVKVFL ISASSKDTGQ LYAALHHRIL ALRS
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: RANBP3 RAN binding protein 3 [ Homo sapiens ]
• Official Symbol: RANBP3
• Synonyms: RANBP3; RAN binding protein 3; ran-binding protein 3; RAN-binding protein-3; DKFZp586I1520
• Gene ID: 8498
• mRNA Refseq: NM_003624
• Protein Refseq: NP_003615
• MIM: 603327
• UniProt ID: Q9H6Z4
• Chromosome Location: 19p13.3
• Pathway: Canonical Wnt signaling pathway, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem
• Function: R-SMAD binding; Ran GTPase binding; protein binding