Recombinant Human EXOSC1, His-tagged
Cat.No. : | EXOSC1-230H |
Product Overview : | EXOSC1, 1-195aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | EXOSC1 is a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Recombinant human EXOSC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT |
Molecular Mass : | 23.8 kDa (218aa) confirmed by MALDI-TOF |
Protein length : | 1-195aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMAPPVRY CIPGERLCNL EEGSPGSGTY TRHGYIFSSL AGCLMKSSEN GALPVVSVVR ETESQLLPDV GAIVTCKVSS INSRFAKVHI LYVGSMPLKN SFRGTIRKED VRATEKDKVE IYKSFRPGDI VLAKVISLGD AQSNYLLTTA ENELGVVVAH SESGIQMVPI SWCEMQCPKT HTKEFRKVAR VQPEFLQT |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/ml (determined by Bradford assay) |
Gene Name : | EXOSC1 exosome component 1 [ Homo sapiens ] |
Official Symbol : | EXOSC1 |
Synonyms : | EXOSC1; exosome component 1; exosome complex component CSL4; CGI 108; CSL4; CSL4 exosomal core protein homolog (yeast); Csl4p; hCsl4p; p13; SKI4; Ski4p; exosomal core protein CSL4; 3-5 exoribonuclease CSL4 homolog; CSL4 exosomal core protein homolog; homolog of yeast exosomal core protein CSL4; CGI-108; RP11-452K12.9; |
Gene ID : | 51013 |
mRNA Refseq : | NM_016046 |
Protein Refseq : | NP_057130 |
MIM : | 606493 |
UniProt ID : | Q9Y3B2 |
Chromosome Location : | 10q24 |
Pathway : | Activation of Genes by ATF4, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by KSRP, organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; |
Function : | RNA binding; NOT exoribonuclease activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
EXOSC1-3566H | Recombinant Human EXOSC1 Protein, GST-tagged | +Inquiry |
Exosc1-2889M | Recombinant Mouse Exosc1 Protein, Myc/DDK-tagged | +Inquiry |
EXOSC1-2901M | Recombinant Mouse EXOSC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
EXOSC1-1345R | Recombinant Rhesus Macaque EXOSC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
EXOSC1-5380M | Recombinant Mouse EXOSC1 Protein | +Inquiry |
◆ Lysates | ||
EXOSC1-6505HCL | Recombinant Human EXOSC1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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