"KSR2" Related Products

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Recombinant Human KSR2 Mutant (R676S), GST-tagged

Cat.No.: KSR2-83H
Product Overview: Recombinant human KSR2 (R676S) (554-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: KSR2 or kinase suppressor of Ras 2 specifically regulates the activity of MEKK3 and COT but not other members of the MAP3K family. KSR interacts with a regulatory Raf molecule in cis to induce a conformational switch of MEK, facilitating MEK"s phosphorylation by a separate catalytic Raf molecule in trans.
Source: Sf9 insect cells using baculovirus
Species: Human
Tag: GST
Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity: The specific activity was determined to be 48 nmol/min/mg
Molecular Mass: ~72 kDa
Purity: >70% by densitometry.
Applications: Kinase Assay
Storage: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration: 0.1 μg/μl
Gene Name: KSR2 kinase suppressor of ras 2 [ Homo sapiens ]
Official Symbol: KSR2
Synonyms: KSR2; kinase suppressor of ras 2; kinase suppressor of Ras 2; FLJ25965;
Gene ID: 283455
mRNA Refseq: NM_173598
Protein Refseq: NP_775869
MIM: 610737
UniProt ID: Q6VAB6
Chromosome Location: 12q24.22-q24.23
Function: ATP binding; metal ion binding; protein serine/threonine kinase activity; transferase activity, transferring phosphorus-containing groups;

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