Recombinant Human ANGPT2, His-tagged, Biotinylated
Cat.No. : | ANGPT2-269H |
Product Overview : | Human Angiopoietin-2 Protein, Biotinylated (Biotinylated ANGPT2) Tyr 19 - Phe 496, was labeled with biotin based on rhANGPT2 Protein, which was produced in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.? |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Trehalose are added as protectants before lyophilization. |
Molecular Mass : | Biotinylated ANGPT2, fused with 6×His tag at the C-terminus, has a calculated MW of 50.1 kDa. The predicted N-terminus is Asp 68 & Tyr 19. DTT-reduced Protein migrates as 66-90 kDa due to glycosylation. |
Endotoxin : | Less than 1.0 EU per μg of the Biotinylated ANGPT2 by the LAL method. |
Purity : | >95% as determined by reduced SDS-PAGE. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). |
Gene Name : | ANGPT2 angiopoietin 2 [ Homo sapiens ] |
Official Symbol : | ANGPT2 |
Synonyms : | ANGPT2; angiopoietin 2; angiopoietin-2; Ang2; ANG-2; Tie2-ligand; angiopoietin-2B; angiopoietin-2a; ANG2; AGPT2; |
Gene ID : | 285 |
mRNA Refseq : | NM_001118887 |
Protein Refseq : | NP_001112359 |
MIM : | 601922 |
UniProt ID : | O15123 |
Chromosome Location : | 8p23 |
Pathway : | Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; Tie2 Signaling, organism-specific biosystem; |
Function : | metal ion binding; protein binding; receptor binding; receptor tyrosine kinase binding; |
Products Types
◆ Recombinant Protein | ||
ANGPT2-1040C | Active Recombinant Canine ANGPT2 protein(Lys274-Phe495), His-tagged | +Inquiry |
Angpt2-2163M | Active Recombinant Mouse Angpt2 Protein, C-6×His tagged | +Inquiry |
ANGPT2-696H | Recombinant Human ANGPT2 Protein, His-tagged | +Inquiry |
ANGPT2-1173C | Active Recombinant Cynomolgus ANGPT2 Protein, His-tagged | +Inquiry |
ANGPT2-325R | Recombinant Rat ANGPT2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ANGPT2-2228HCL | Recombinant Human ANGPT2 cell lysate | +Inquiry |
ANGPT2-001MCL | Recombinant Mouse ANGPT2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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