"EPCAM" Related Products

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Recombinant Human EPCAM, His-tagged, Biotinylated

Cat.No.: EPCAM-276H
Product Overview: Human EpCAM /CD326 Protein, Biotinylated (Biotinylated EpCAM) Gln 24 - Lys 265, was labeled with biotin based on rhEpCAM Protein, which was produced in human 293 cells (HEK293).
Description: This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
Source: HEK293
Species: Human
Tag: His
Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Trehalose are added as protectants before lyophilization.
Molecular Mass: Biotinylated EpCAM, fused with 6×His tag at the C-terminus, has a calculated MW of 29 kDa. The predicted N-terminus is Gln 24. DTT-reduced Protein migrates as 33-36 kDa due to glycosylation.
Endotoxin: Less than 1.0 EU per μg of the Biotinylated EpCAM by the LAL method.
Purity: >95% as determined by reduced SDS-PAGE.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C).
Gene Name: EPCAM epithelial cell adhesion molecule [ Homo sapiens ]
Official Symbol: EPCAM
Synonyms: EPCAM; epithelial cell adhesion molecule; antigen identified by monoclonal AUA1 , M4S1, MIC18, TACSTD1, tumor associated calcium signal transducer 1; 17 1A; 323/A3; CD326; CO 17A; EGP 2; EGP34; EGP40; Ep CAM; ESA; GA733 2; HEA125; KS1/4; KSA; Ly74; MH99; MK 1; MOC31; TACST 1; TROP1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); M4S1; MK-1; DIAR5; EGP-2; MIC18; EGP314; HNPCC8; TACSTD1; GA733-2;
Gene ID: 4072
mRNA Refseq: NM_002354
Protein Refseq: NP_002345
MIM: 185535
UniProt ID: P16422
Chromosome Location: 2p21
Function: protein binding;

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