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Recombinant Human PAICS, His-tagged

Cat.No.: PAICS-1511H
Product Overview: Recombinant Human PAICS protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Source: E.coli
Species: Human
Tag: His
Protein length: C-term-350aa
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase [ Homo sapiens ]
Official Symbol: PAICS
Synonyms: PAICS; phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase; PAIS; multifunctional protein ADE2; ADE2H1; AIRC; AIR carboxylase; SAICAR synthetase; multifunctional protein ADE2H1; ADE2; MGC1343; MGC5024; DKFZp781N1372;
Gene ID: 10606
mRNA Refseq: NM_001079524
Protein Refseq: NP_001072992
MIM: 172439
UniProt ID: P22234
Chromosome Location: 4q12
Pathway: Inosine monophosphate biosynthesis, PRPP + glutamine =>IMP, organism-specific biosystem; Inosine monophosphate biosynthesis, PRPP + glutamine => IMP, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem;
Function: 5-(carboxyamino)imidazole ribonucleotide mutase activity; ATP binding; identical protein binding; ligase activity; lyase activity; nucleotide binding; phosphoribosylaminoimidazole carboxylase activity; phosphoribosylaminoimidazolesuccinocarboxamide syntha

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