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Recombinant Human RNF133, His-tagged

Cat.No. : RNF133-2337H
Product Overview : Recombinant Human RNF133 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
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Source : E.coli
Species : Human
Tag : His
Protein length : C-169aa
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : RNF133 ring finger protein 133 [ Homo sapiens ]
Official Symbol : RNF133
Synonyms : RNF133; ring finger protein 133; E3 ubiquitin-protein ligase RNF133; MGC27072;
Gene ID : 168433
mRNA Refseq : NM_139175
Protein Refseq : NP_631914
UniProt ID : Q8WVZ7
Chromosome Location : 7q31.33
Function : ligase activity; metal ion binding; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Does RNF133 interact with other proteins or molecules? 11/20/2022

The interaction of RNF133 with other proteins or molecules is not fully understood. However, based on its structural and functional characteristics, it can be speculated that it may interact with some enzymes, transcription factors, or other signal transduction molecules to participate in the intracellular protein degradation process.

Can RNF133 mutations affect cells? 04/17/2022

Mutations in RNF133 may have a variety of effects on cells, such as affecting intracellular protein degradation, leading to abnormal cell proliferation, and inducing apoptosis. These effects may be related to the occurrence of some diseases, such as neurological diseases, cancer, etc.

How can the interaction network of RNF133 be studied? 01/05/2022

Molecular biology and biochemical methods, such as yeast two-hybridization, affinity chromatography, mass spectrometry, etc., can be used to study the interaction network of RNF133. These methods can help us understand the function and mechanism of action of RNF133 in cells.

Is there an application of RNF133 in disease diagnosis and treatment? 01/03/2022

RNF133 can be used as a biomarker for disease diagnosis and as a therapeutic target. For example, by detecting the expression levels or mutations of RNF133, doctors can be able to diagnose and evaluate the prognosis of certain diseases, and treatment strategies for RNF133 can also provide patients with more effective treatment options.

What factors are associated with RNF133 expression levels? 02/24/2021

The expression level of RNF133 may be affected by a variety of factors, such as gene mutations, transcription factors, nutrients, etc. These factors may regulate the expression level of RNF133 by influencing its transcription and translation processes.

How to construct cell models with RNF133 overexpression or knockdown? 01/21/2020

Cell models with overexpression or knockout of RNF133 can be established by gene transfection. The vector of the gene of interest or a specific knockout gene is introduced into the cells, and the stably expressed or knocked out cell line is obtained through screening and identification.

Customer Reviews (3)

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02/16/2022

    Easy to purify and manipulate, easy to store, and easy to use.

    10/05/2020

      The results are reliable and trustworthy.

      07/25/2020

        RNF133 is easy to prepare, so we can easily prepare it ourselves.

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