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Recombinant Human RNGTT, GST-tagged

Cat.No. : RNGTT-2349H
Product Overview : Recombinant Human RNGTT protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Source : E.coli
Species : Human
Tag : GST
Protein length : C-term-356aa
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : RNGTT RNA guanylyltransferase and 5-phosphatase [ Homo sapiens ]
Official Symbol : RNGTT
Synonyms : RNGTT; RNA guanylyltransferase and 5-phosphatase; mRNA-capping enzyme; hCAP; HCE; HCE1; HCAP1; CAP1A; DKFZp686J2031;
Gene ID : 8732
mRNA Refseq : NM_003800
Protein Refseq : NP_003791
MIM : 603512
UniProt ID : O60942
Chromosome Location : 6q16
Pathway : Disease, organism-specific biosystem; Gene Expression, organism-specific biosystem; HIV Infection, organism-specific biosystem; HIV Life Cycle, organism-specific biosystem; Late Phase of HIV Life Cycle, organism-specific biosystem; RNA Pol II CTD phosphor
Function : GTP binding; hydrolase activity; mRNA guanylyltransferase activity; nucleotide binding; nucleotidyltransferase activity; phosphatase activity; polynucleotide 5-phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can RNGTT protein-based therapies be used in personalized medicine? 07/30/2020

There is potential for RNGTT protein-based therapies to be tailored to individual patients based on their specific disease characteristics.

How can RNGTT protein be targeted for clinical therapy? 06/29/2020

Targeting RNGTT protein may offer potential therapeutic strategies for autoimmune diseases and cancer.

Can RNGTT protein be targeted for the treatment of neurodegenerative diseases? 03/26/2020

There is emerging research exploring the potential of targeting RNGTT protein in the context of neurodegenerative diseases.

How does RNGTT protein relate to the development of autoimmune diseases? 07/15/2018

Dysregulation of protein glycosylation mediated by RNGTT protein has been implicated in the pathogenesis of autoimmune diseases.

What are the potential clinical implications of RNGTT protein deficiency? 10/05/2016

RNGTT protein deficiency can lead to a range of disorders, including immune system dysregulation and developmental defects.

Customer Reviews (3)

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04/04/2023

    Its exceptional characteristics, coupled with the manufacturer's commitment to customer satisfaction, ensure that I can pursue my scientific investigations with confidence and success.

    07/09/2022

      This level of support becomes invaluable, allowing researchers to focus on their scientific objectives while receiving expert guidance alongside.

      08/07/2020

        Its consistent performance and reproducibility have been praised by scientists who have employed it in their studies, with many reporting outstanding results and a high level of satisfaction.

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