Recombinant Human BTD, MYC/DDK-tagged BTD-8393H

Recombinant Human BTD, MYC/DDK-tagged


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Recombinant Human BTD, MYC/DDK-tagged

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Cat.No. : BTD-8393H
Product Overview : Recombinant Human BTD fused with C-terminal MYC/DDK, was expressed in HEK293 Cells.
Description : The protein encoded by this gene functions to recycle protein-bound biotin by cleaving biocytin (biotin-epsilon-lysine), a normal product of carboxylase degradation, resulting in regeneration of free biotin. The encoded protein has also been shown to have biotinyl transferase activity. Mutations in this gene are associated with biotinidase deficiency. Multiple transcript variants encoding different isoforms have been described.
Source : HEK293
Species : Human
Molecular Mass : 56.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : BTD biotinidase [ Homo sapiens (human) ]
Official Symbol : BTD
Synonyms : BTD; biotinidase; biotinase; NP_000051.1; NP_001268652.1; NP_001268653.1; NP_001268654.1; NP_001268655.1; EC
Gene ID : 686
mRNA Refseq : NM_000060
Protein Refseq : NP_000051
MIM : 609019
UniProt ID : P43251
Chromosome Location : 3p25
Pathway : Defects in vitamin and cofactor metabolism; Metabolism of vitamins and cofactors; Metabolism of water-soluble vitamins and cofactors
Function : biotin carboxylase activity; biotinidase activity

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