Recombinant Human UNG protein, GST-tagged

• Cat.No.: UNG-3600H
• Product Overview: Recombinant Human UNG protein(P13051-2) (Phe 85-Leu 304) was expressed in E.coli, fused with the GST tag at the N-terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 85-304 aa
• Form: Lyophilized from sterile 40mM Tris, 0.15M NaCl, 2mM GSH, pH 7.5.
• Molecular Mass: The recombinant human UNG/GST chimera consists of 452 amino acids and has a predicted molecular mass of 52 kDa. It migrates as an approxiamtely 48 kDa band in SDS-PAGE under reducing conditions.
• Purity: > 90 % as determined by SDS-PAGE
• Storage: Store it under sterile conditions at -20°C to -80°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
• Publications:
  • An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation (2021)

Gene Information

• Gene Name: UNG uracil-DNA glycosylase [ Homo sapiens ]
• Official Symbol: UNG
• Synonyms: UNG; uracil-DNA glycosylase; DGU; HIGM4; UDG; UNG1; UNG2; uracil DNA glycosylase 1; uracil DNA glycosylase 2; uracil-DNA glycosylase 1, uracil-DNA glycosylase 2; UNG15; DKFZp781L1143
• Gene ID: 7374
• mRNA Refseq: NM_003362
• Protein Refseq: NP_003353
• MIM: 191525
• UniProt ID: P13051