Recombinant Human UNG, GST-tagged

• Cat.No.: UNG-3600H
• Product Overview: Recombinant Human UNG protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-304aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
• Publications:
  An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation (2021)

Gene Information

• Gene Name: UNG uracil-DNA glycosylase [ Homo sapiens ]
• Official Symbol: UNG
• Synonyms: UNG; uracil-DNA glycosylase; DGU; HIGM4; UDG; UNG1; UNG2; uracil DNA glycosylase 1; uracil DNA glycosylase 2; uracil-DNA glycosylase 1, uracil-DNA glycosylase 2; UNG15; DKFZp781L1143
• Gene ID: 7374
• mRNA Refseq: NM_003362
• Protein Refseq: NP_003353
• MIM: 191525
• UniProt ID: P13051
• Chromosome Location: 12q23-q24.1
• Pathway: Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Primary immunodeficiency, organism-specific biosystem; Primary immunodeficiency, conserved biosystem
• Function: hydrolase activity, hydrolyzing N-glycosyl compounds; uracil DNA N-glycosylase activity; uracil DNA N-glycosylase activity