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Recombinant Human TSHR, GST-tagged

Cat.No. : TSHR-3450H
Product Overview : Recombinant Human TSHR was expressed as gst-tagged fusion protein by E.Coli and puri?ed by GSH-sepharose.
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Description : The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
Source : E.coli
Species : Human
Tag : GST
Protein length : False
AA Sequence : 1-253aa
Storage : The protein is stored in PBS bu?er at -20 oC. Repeated freeze-thaw cycles should be avoided.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : TSHR?thyroid stimulating hormone receptor [?Homo sapiens?(human) ]
Official Symbol : TSHR
Synonyms : TSHR; LGR3; CHNG1; hTSHR-I; thyroid stimulating hormone receptor; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2
Gene ID : 7253
mRNA Refseq : NM_000369
Protein Refseq : NP_000360
MIM : 603372
UniProt ID : P16473
Chromosome Location : 14q31
Pathway : Arf6 signaling events; Autoimmune thyroid disease; G alpha (s) signalling events
Function : protein binding; thyroid-stimulating hormone receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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