Recombinant Human TSHR, GST-tagged
Cat.No. : | TSHR-3450H |
Product Overview : | Recombinant Human TSHR was expressed as gst-tagged fusion protein by E.Coli and puri?ed by GSH-sepharose. |
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Description : | The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | False |
AA Sequence : | 1-253aa |
Storage : | The protein is stored in PBS bu?er at -20 oC. Repeated freeze-thaw cycles should be avoided. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | TSHR?thyroid stimulating hormone receptor [?Homo sapiens?(human) ] |
Official Symbol : | TSHR |
Synonyms : | TSHR; LGR3; CHNG1; hTSHR-I; thyroid stimulating hormone receptor; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2 |
Gene ID : | 7253 |
mRNA Refseq : | NM_000369 |
Protein Refseq : | NP_000360 |
MIM : | 603372 |
UniProt ID : | P16473 |
Chromosome Location : | 14q31 |
Pathway : | Arf6 signaling events; Autoimmune thyroid disease; G alpha (s) signalling events |
Function : | protein binding; thyroid-stimulating hormone receptor activity |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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