"TSHR" Related Products

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Recombinant Human TSHR, GST-tagged

Cat.No.: TSHR-3450H
Product Overview: Recombinant Human TSHR was expressed as gst-tagged fusion protein by E.Coli and puri?ed by GSH-sepharose.
Description: The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
Source: E.coli
Species: Human
Tag: GST
Protein length: False
AA Sequence: 1-253aa
Storage: The protein is stored in PBS bu?er at -20 oC. Repeated freeze-thaw cycles should be avoided.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: TSHR?thyroid stimulating hormone receptor [?Homo sapiens?(human) ]
Official Symbol: TSHR
Synonyms: TSHR; LGR3; CHNG1; hTSHR-I; thyroid stimulating hormone receptor; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2
Gene ID: 7253
mRNA Refseq: NM_000369
Protein Refseq: NP_000360
MIM: 603372
UniProt ID: P16473
Chromosome Location: 14q31
Pathway: Arf6 signaling events; Autoimmune thyroid disease; G alpha (s) signalling events
Function: protein binding; thyroid-stimulating hormone receptor activity

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