Recombinant Human ZEB1, GST-tagged
Cat.No. : | ZEB1-3796H |
Product Overview : | Recombinant Human ZEB1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 391-740aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ZEB1 zinc finger E-box binding homeobox 1 [ Homo sapiens ] |
Official Symbol : | ZEB1 |
Synonyms : | ZEB1; zinc finger E-box binding homeobox 1; posterior polymorphous corneal dystrophy 3 , PPCD3, TCF8, transcription factor 8 (represses interleukin 2 expression); zinc finger E-box-binding homeobox 1; AREB6; BZP; NIL 2 A; ZEB; Zfhep; Zfhx1a; negative regulator of IL2; delta-crystallin enhancer binding factor 1; posterior polymorphous corneal dystrophy 3; zinc finger homeodomain enhancer-binding protein; transcription factor 8 (represses interleukin 2 expression); TCF8; FECD6; NIL2A; PPCD3; ZFHEP; ZFHX1A; DELTAEF1; MGC133261; |
Gene ID : | 6935 |
mRNA Refseq : | NM_001128128 |
Protein Refseq : | NP_001121600 |
MIM : | 189909 |
UniProt ID : | P37275 |
Chromosome Location : | 10p11.22 |
Pathway : | Hypertrophy Model, organism-specific biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem; |
Function : | E-box binding; E-box binding; chromatin binding; double-stranded DNA binding; metal ion binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription |
Products Types
◆ Recombinant Protein | ||
ZEB1-604H | Recombinant Human ZEB1 Protein, His-tagged | +Inquiry |
ZEB1-10324M | Recombinant Mouse ZEB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ZEB1-6688C | Recombinant Chicken ZEB1 | +Inquiry |
ZEB1-22H | Recombinant Human ZEB1 Protein, GST-tagged | +Inquiry |
ZEB1-18798M | Recombinant Mouse ZEB1 Protein | +Inquiry |
◆ Lysates | ||
ZEB1-190HCL | Recombinant Human ZEB1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionClinical studies have indicated a correlation between high ZEB1 expression and reduced overall survival rates in cancer patients.
Some research is focused on developing inhibitors targeting ZEB1 as potential therapeutic agents, although this area is still in the early stages.
ZEB1 promotes the invasion and metastasis of cancer cells by inducing EMT, allowing cells to acquire a more migratory and invasive phenotype.
Targeting ZEB1 for personalized medicine approaches is an area of active research, exploring its potential as a specific therapeutic target based on individual patient profiles.
Emerging evidence suggests that assessing ZEB1 expression levels may have diagnostic potential, especially in identifying early stages of certain cancers.
Customer Reviews (3)
Write a reviewThey provide comprehensive assistance, ensuring that any queries or concerns I have regarding the ZEB1 protein are promptly addressed.
One of the standout advantages offered by the manufacturer is their excellent technical support.
They continuously stay up-to-date with the latest scientific advancements and customer feedback, allowing them to refine the ZEB1 protein based on emerging trends.
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