Gene Name |
ZEB1 zinc finger E-box binding homeobox 1 [ Homo sapiens ] |
Official Symbol |
ZEB1 |
Synonyms |
ZEB1; zinc finger E-box binding homeobox 1; posterior polymorphous corneal dystrophy 3 , PPCD3, TCF8, transcription factor 8 (represses interleukin 2 expression); zinc finger E-box-binding homeobox 1; AREB6; BZP; NIL 2 A; ZEB; Zfhep; Zfhx1a; negative regulator of IL2; delta-crystallin enhancer binding factor 1; posterior polymorphous corneal dystrophy 3; zinc finger homeodomain enhancer-binding protein; transcription factor 8 (represses interleukin 2 expression); TCF8; FECD6; NIL2A; PPCD3; ZFHEP; ZFHX1A; DELTAEF1; MGC133261; |
Gene ID |
6935 |
mRNA Refseq |
NM_001128128 |
Protein Refseq |
NP_001121600 |
MIM |
189909 |
UniProt ID |
P37275 |
Chromosome Location |
10p11.22 |
Pathway |
Hypertrophy Model, organism-specific biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem; |
Function |
E-box binding; E-box binding; chromatin binding; double-stranded DNA binding; metal ion binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription |