Recombinant Human GYS1, MYC/DDK-tagged
Cat.No. : | GYS1-11H |
Product Overview : | Recombinant Human GYS1, fused with C-terminal MYC/DDK, was expressed in HEK293. |
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- Gene Information
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Description : | The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Molecular Mass : | 83.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | GYS1 glycogen synthase 1 (muscle) [ Homo sapiens (human) ] |
Official Symbol : | GYS1 |
Synonyms : | GYS1; GSY; GYS; glycogen synthase 1 (muscle); glycogen [starch] synthase, muscle; NP_001155059.1; EC 2.4.1.11; NP_002094.2 |
Gene ID : | 2997 |
mRNA Refseq : | NM_002103 |
Protein Refseq : | NP_002094 |
MIM : | 138570 |
UniProt ID : | P13807 |
Chromosome Location : | 19q13.3 |
Pathway : | Glucose metabolism; Insulin Signaling; Metabolism of carbohydrates |
Function : | glucose binding; glycogen (starch) synthase activity; glycogen synthase activity, transferring glucose-1-phosphate |
Products Types
◆ Recombinant Protein | ||
Gys1-1082M | Recombinant Mouse Gys1 Protein, MYC/DDK-tagged | +Inquiry |
GYS1-4021M | Recombinant Mouse GYS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
GYS1-2422R | Recombinant Rat GYS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
GYS1-1843R | Recombinant Rhesus Macaque GYS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
GYS1-2768R | Recombinant Rat GYS1 Protein | +Inquiry |
◆ Lysates | ||
GYS1-5670HCL | Recombinant Human GYS1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionIt plays a significant role in maintaining blood glucose levels by regulating glycogen synthesis in response to hormonal signals.
Targeting GYS1 could provide new strategies for managing metabolic conditions, including glycogen storage diseases and diabetes.
Genetic mutations in GYS1 can lead to glycogen storage diseases, affecting glucose availability and energy balance.
GYS1, Glycogen Synthase 1, is crucial for the synthesis of glycogen, the primary storage form of glucose in the body.
Altered GYS1 activity can impact glycogen storage and glucose metabolism, contributing to disorders like diabetes.
GYS1 is vital for muscle and liver function, where it facilitates energy storage and release.
GYS1's activity is regulated by insulin and glucagon, which modulate glycogen synthesis in response to the body's energy needs.
Customer Reviews (3)
Write a reviewCritical for research success. Consistently trustworthy.
Dependable service. A research must-have.
Reliable data source. Elevates our research quality.
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