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Recombinant Human GYS1, MYC/DDK-tagged

Cat.No. : GYS1-11H
Product Overview : Recombinant Human GYS1, fused with C-terminal MYC/DDK, was expressed in HEK293.
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Description : The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Molecular Mass : 83.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : GYS1 glycogen synthase 1 (muscle) [ Homo sapiens (human) ]
Official Symbol : GYS1
Synonyms : GYS1; GSY; GYS; glycogen synthase 1 (muscle); glycogen [starch] synthase, muscle; NP_001155059.1; EC 2.4.1.11; NP_002094.2
Gene ID : 2997
mRNA Refseq : NM_002103
Protein Refseq : NP_002094
MIM : 138570
UniProt ID : P13807
Chromosome Location : 19q13.3
Pathway : Glucose metabolism; Insulin Signaling; Metabolism of carbohydrates
Function : glucose binding; glycogen (starch) synthase activity; glycogen synthase activity, transferring glucose-1-phosphate

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does GYS1 contribute to the regulation of blood glucose levels? 10/29/2022

It plays a significant role in maintaining blood glucose levels by regulating glycogen synthesis in response to hormonal signals.

What potential therapeutic applications could arise from targeting GYS1 in metabolic diseases? 08/29/2022

Targeting GYS1 could provide new strategies for managing metabolic conditions, including glycogen storage diseases and diabetes.

How do genetic mutations in the GYS1 gene affect glycogen storage and metabolism? 07/12/2022

Genetic mutations in GYS1 can lead to glycogen storage diseases, affecting glucose availability and energy balance.

What is the primary role of GYS1 in glycogen synthesis? 05/22/2022

GYS1, Glycogen Synthase 1, is crucial for the synthesis of glycogen, the primary storage form of glucose in the body.

What is the impact of altered GYS1 activity on metabolic disorders like diabetes? 10/24/2020

Altered GYS1 activity can impact glycogen storage and glucose metabolism, contributing to disorders like diabetes.

What role does GYS1 play in muscle and liver function? 10/12/2019

GYS1 is vital for muscle and liver function, where it facilitates energy storage and release.

How does GYS1 interact with hormonal signals like insulin and glucagon in glycogen metabolism? 12/30/2017

GYS1's activity is regulated by insulin and glucagon, which modulate glycogen synthesis in response to the body's energy needs.

Customer Reviews (3)

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Reviews
08/29/2022

    Critical for research success. Consistently trustworthy.

    10/24/2020

      Dependable service. A research must-have.

      12/30/2017

        Reliable data source. Elevates our research quality.

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