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Recombinant Human coxsackie virus and adenovirus receptor, His-tagged

Cat.No. : CXADR-247H
Product Overview : CXADR, 20-237aa, Human, His tag, E.coli
  • Specification
  • Gene Information
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Description : CXADR is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. Recombinant human CXADR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source : E.coli
Species : Human
Tag : His-tag
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT.
Molecular Mass : 26 kDa (241aa), confirmed by MALDI-TOF
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSLSITTPE EMIEKAKGET AYLPCKFTLS PEDQGPLDIE WLISPADNQK VDQVIILYSG DKIYDDYYPD LKGRVHFTSN DLKSGDASIN VTNLQLSDIG TYQCKVKKAP GVANKKIHLV VLVKPSGARC YVDGSEEIGS DFKIKCEPKE GSLPLQYEWQ KLSDSQKMPT SWLAEMTSSV ISVKNASSEY SGTYSCTVRN RVGSDQCLLR LNVVPPSNKA G
Purity : >90% by SDS - PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Bradford assay)
Gene Name : CXADR coxsackie virus and adenovirus receptor [ Homo sapiens ]
Official Symbol : CXADR
Synonyms : CXADR; coxsackie virus and adenovirus receptor; coxsackievirus and adenovirus receptor; CAR; HCVADR; CVB3-binding protein; coxsackievirus B-adenovirus receptor; 46 kD coxsackievirus and adenovirus receptor (CAR) protein; HCAR; CAR4/6;
Gene ID : 1525
mRNA Refseq : NM_001207063
Protein Refseq : NP_001193992
MIM : 602621
UniProt ID : P78310
Chromosome Location : 21q21.1
Pathway : Adaptive Immune System, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Viral myocarditis, organism-specific biosystem;
Function : PDZ domain binding; beta-catenin binding; cell adhesion molecule binding; connexin binding; identical protein binding; protein binding; receptor activity; receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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