Recombinant Human Bartter syndrome, infantile, with sensorineural deafness (Barttin), His-tagged
Cat.No. : | BSND-250H |
Product Overview : | BSND, 54-320aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | BSND is an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this BSND have been associated with Bartter syndrome with sensorineural deafness. Recombinant human BSND protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT |
Molecular Mass : | 31.7 kDa (290aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSCQCYPKI TFVPADSDFQ GILSPKAMGL LENGLAAEMK SPSPQPPYVR LWEEAAYDQS LPDFSHIQMK VMSYSEDHRS LLAPEMGQPK LGTSDGGEGG PGDVQAWMEA AVVIHKGSDE SEGERRLTQS WPGPLACPQG PAPLASFQDD LDMDSSEGSS PNASPHDREE ACSPQQEPQG CRCPLDRFQD FALIDAPTLE DEPQEGQQWE IALPNNWQRY PRTKVEEKEA SDTGGEEPEK EEEDLYYGLP DGAGDLLPDK ELGFEPDTQG |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25mg/ml (determined by Bradford assay) |
Gene Name : | BSND Bartter syndrome, infantile, with sensorineural deafness (Barttin) [ Homo sapiens ] |
Official Symbol : | BSND |
Synonyms : | BSND; Bartter syndrome, infantile, with sensorineural deafness (Barttin); deafness, autosomal recessive 73 , DFNB73; barttin; BART; deafness, autosomal recessive 73; DFNB73; MGC119283; MGC119284; MGC119285; |
Gene ID : | 7809 |
mRNA Refseq : | NM_057176 |
Protein Refseq : | NP_476517 |
MIM : | 606412 |
UniProt ID : | Q8WZ55 |
Chromosome Location : | 1p32.3 |
Function : | contributes_to chloride channel activity; chloride channel regulator activity; |
Products Types
◆ Recombinant Protein | ||
BSND-681R | Recombinant Rat BSND Protein, His (Fc)-Avi-tagged | +Inquiry |
BSND-1099M | Recombinant Mouse BSND Protein, His (Fc)-Avi-tagged | +Inquiry |
BSND-10305H | Recombinant Human BSND, GST-tagged | +Inquiry |
BSND-1023R | Recombinant Rat BSND Protein | +Inquiry |
BSND-360H | Recombinant Human BSND Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
BSND-8401HCL | Recombinant Human BSND 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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