Recombinant Human ER lipid raft associated 2, His-tagged

• Cat.No.: ERLIN2-343H
• Product Overview: ERLIN2, 25-339aa, Human, His tag, E.coli

Specification

• Description: ERLIN2, also known as SPFH2, is SPFH domain-containing proteins that belong to the prohibitin family. Also, this protein is a ubiquitously expressed 339 amino acid protein that belongs to the band 7/mec-2 family. Localized to lipid raft-like domains in the membrane of the endoplasmic reticulum (ER), ERLIN2 plays a crucial role in the ER-associated degradation (ERAD) pathway that removes metabolically regulated and aberrant proteins from the ER. Recombinant human ERLIN2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M Urea, 20% glycerol
• Molecular Mass: 37.8 kDa (338aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSKIEEGHI GVYYRGGALL TSTSGPGFHL MLPFITSYKS VQTTLQTDEV KNVPCGTSGG VMIYFDRIEV VNFLVPNAVY DIVKNYTADY DKALIFNKIH HELNQFCSVH TLQEVYIELF DQIDENLKLA LQQDLTSMAP GLVIQAVRVT KPNIPEAIRR NYELMESEKT KLLIAAQKQK VVEKEAETER KKALIEAEKV AQVAEITYGQ KVMEKETEKK ISEIEDAAFL AREKAKADAE CYTAMKIAEA NKLKLTPEYL QLMKYKAIAS NSKIYFGKDI PNMFMDSAGS VSKQFEGLAD KLSFGLEDEP LETATKEN
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ERLIN2 ER lipid raft associated 2 [ Homo sapiens ]
• Official Symbol: ERLIN2
• Synonyms: ERLIN2; ER lipid raft associated 2; C8orf2, chromosome 8 open reading frame 2 , Erlin 2, SPFH domain family, member 2 , SPFH2; erlin-2; NET32; SPFH domain family, member 2; endoplasmic reticulum lipid raft-associated protein 2; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2; SPFH2; SPG18; C8orf2; Erlin-2; MGC87072
• Gene ID: 11160
• mRNA Refseq: NM_001003790
• Protein Refseq: NP_001003790
• MIM: 611605
• UniProt ID: O94905
• Chromosome Location: 8p11.2
• Function: protein binding