Recombinant Human steroid receptor RNA activator 1, His-tagged SRA1-357H

Recombinant Human steroid receptor RNA activator 1, His-tagged

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Recombinant Human steroid receptor RNA activator 1, His-tagged

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Cat.No. : SRA1-357H
Product Overview : SRA1, 90-236aa, Human, His tag, E.coli
Description : Steroid receptor RNA activator 1, also known as SRA1, exists as both a RNA transcript and as stably expressed proteins. Also this protein mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). SRA1 enhances cellular proliferation and differentiation and promotes apoptosis in vivo. It may play a role in tumorigenesis. Recombinant human SRA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source : E.coli
Species : Human
Tag : His-tag
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT
Molecular Mass : 18.7 kDa (170aa) confirmed by MALDI-TOF
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSVGSGPAS GVEPTSFPVE SEAVMEDVLR PLEQALEDCR GHTRKQVCDD ISRRLALLQE QWAGGKLSIP VKKRMALLVQ ELSSHRWDAA DDIHRSLMVD HVTEVSQWMV GVKRLIAEKR SLFSEEAANE EKSAATAEKN HTIPGFQQAS
Purity : >85% by SDS - PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : Lanz R B., et al. (1999) Cell. 97:17-27Watanabe M., et al. (2001) EMBO J. 20: 1341-1352.
Gene Name : SRA1 steroid receptor RNA activator 1 [ Homo sapiens ]
Official Symbol : SRA1
Synonyms : SRA1; steroid receptor RNA activator 1; steriod receptor RNA activator 1; SRA; STRAA1; steroid receptor coactivator; steroid receptor RNA activator protein; steroid receptor RNA activator 1 (complexes with NCOA1); SRAP; pp7684; MGC87674;
Gene ID : 10011
mRNA Refseq : NM_001035235
Protein Refseq : NP_001030312
MIM : 603819
UniProt ID : Q9HD15
Chromosome Location : 5q31
Function : DNA binding; ligand-dependent nuclear receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; receptor activity; thyroid hormone receptor activator activity; transcription coactivator activity;

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