Recombinant Human steroid receptor RNA activator 1, His-tagged


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Recombinant Human steroid receptor RNA activator 1, His-tagged

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Cat.No. : SRA1-357H
Product Overview : SRA1, 90-236aa, Human, His tag, E.coli
Description : Steroid receptor RNA activator 1, also known as SRA1, exists as both a RNA transcript and as stably expressed proteins. Also this protein mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). SRA1 enhances cellular proliferation and differentiation and promotes apoptosis in vivo. It may play a role in tumorigenesis. Recombinant human SRA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source : E.coli
Species : Human
Tag : His-tag
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT
Molecular Mass : 18.7 kDa (170aa) confirmed by MALDI-TOF
Purity : >85% by SDS - PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : Lanz R B., et al. (1999) Cell. 97:17-27Watanabe M., et al. (2001) EMBO J. 20: 1341-1352.
Gene Name : SRA1 steroid receptor RNA activator 1 [ Homo sapiens ]
Official Symbol : SRA1
Synonyms : SRA1; steroid receptor RNA activator 1; steriod receptor RNA activator 1; SRA; STRAA1; steroid receptor coactivator; steroid receptor RNA activator protein; steroid receptor RNA activator 1 (complexes with NCOA1); SRAP; pp7684; MGC87674;
Gene ID : 10011
mRNA Refseq : NM_001035235
Protein Refseq : NP_001030312
MIM : 603819
UniProt ID : Q9HD15
Chromosome Location : 5q31
Function : DNA binding; ligand-dependent nuclear receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; receptor activity; thyroid hormone receptor activator activity; transcription coactivator activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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