Recombinant Human basic leucine zipper transcription factor, ATF-like 3, His-tagged

• Cat.No.: BATF3-468H
• Product Overview: BATF3, 1-127aa Human, His tag, E.coli

Specification

• Description: Basic leucine zipper transcriptional factor ATF-like 3, also known as BATF3, is a 127 amino acid protein that localizes to the nucleus and contains one bZIP domain. Interacting with c-Jun, BATF3 functions as a negative regulator of AP-1-mediated transcription, specifically by heterodimerizing with c-Jun and binding to DNA response elements. Recombinant human BATF3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol
• Molecular Mass: 16.9 kDa (150aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSQGLPA AGSVLQRSVA APGNQPQPQP QQQSPEDDDR KVRRREKNRV AAQRSRKKQT QKADKLHEEY ESLEQENTML RREIGKLTEE LKHLTEALKE HEKMCPLLLC PMNFVPVPPR PDPVAGCLPR
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by BCA assay)

Gene Information

• Gene Name: BATF3 basic leucine zipper transcription factor, ATF-like 3 [ Homo sapiens ]
• Official Symbol: BATF3
• Synonyms: BATF3; basic leucine zipper transcription factor, ATF-like 3; basic leucine zipper transcriptional factor ATF-like 3; JDP1; Jun dimerization protein 1; JUNDM1; SNFT; B-ATF-3; Jun dimerization protein p21SNFT; 21-kD small nuclear factor isolated from T cells; 21 kDa small nuclear factor isolated from T-cells; FLJ36352; FLJ37535
• Gene ID: 55509
• mRNA Refseq: NM_018664
• Protein Refseq: NP_061134
• MIM: 612470
• UniProt ID: Q9NR55
• Chromosome Location: 1q32.3
• Pathway: Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem
• Function: protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription corepressor activity