Recombinant Human nudix (nucleoside diphosphate linked moiety X)-type motif 4, His-tagged

• Cat.No.: NUDT4-585H
• Product Overview: NUDT4, 1-180aa, Human, His tag, E.coli

Specification

• Description: NUDT4 regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to regulating intracellular trafficking. Recombinant human NUDT4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
• Molecular Mass: 22.7kDa (203aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMMKFKPN QTRTYDREGF KKRAACLCFR SEQEDEVLLV SSSRYPDQWI VPGGGMEPEE EPGGAAVREV YEEAGVKGKL GRLLGIFENQ DRKHRTYVYV LTVTEILEDW EDSVNIGRKR EWFKVEDAIK VLQCHKPVHA EYLEKLKLGC SPANGNSTVP SLPDNNALFV TAAQTSGLPS SVR
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 [ Homo sapiens ]
• Official Symbol: NUDT4
• Synonyms: NUDT4; nudix (nucleoside diphosphate linked moiety X)-type motif 4; diphosphoinositol polyphosphate phosphohydrolase 2; diphosphoinositol polyphosphate phosphohydrolase type 2; DIPP2; DIPP2alpha; DIPP2beta; HDCMB47P; KIAA0487; DIPP-2; diadenosine 5,5-P1,P6-hexaphosphate hydrolase 2; DKFZp686I1281
• Gene ID: 11163
• mRNA Refseq: NM_019094
• Protein Refseq: NP_061967
• MIM: 609229
• UniProt ID: Q9NZJ9
• Chromosome Location: 12q21
• Function: diphosphoinositol-polyphosphate diphosphatase activity; hydrolase activity; inositol diphosphate tetrakisphosphate diphosphatase activity; inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity; inositol-1,5-bisdiphosphate-2,3,4,6-